Precision medicine in ophthalmology: An evolving revolution in diagnostic and therapeutic tools

Marina Roizenblatt, Jaime Roizenblatt, Kim Jiramongkolchai, Peter Louis Gehlbach, Rodrigo Brant, Mauricio Maia, Rubens Belfort

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Precision medicine refers to a stratification of patients using a wide array of individual-specific data to enable precise targeting of disease subgroups with the best available diagnostic and therapeutic approaches. Within ophthalmology, this strategy is being applied successfully and is most evident in the management of the inherited diseases. This paradigm shift in provision of care is accelerated by the emergence of novel imaging technologies, robotics, and artificial intelligence, as well as emerging technologies that integrate bioinformatics data into clinically relevant knowledge. This knowledge is used in turn to develop a system capable of supporting clinical decision-making and utilization of high-precision therapeutic options in both a personalized and cost-effective way. Examples of the diverse areas making rapid progress toward full implementation of precision medicine include, but are not limited to, ocular genetic diseases, robotic surgery, virtual reality simulations, modern imaging techniques, and the role of healthcare providers.

Original languageEnglish (US)
Title of host publicationPrecision Medicine for Investigators, Practitioners and Providers
PublisherElsevier
Pages361-368
Number of pages8
ISBN (Electronic)9780128191781
DOIs
StatePublished - Jan 1 2019

Keywords

  • Imaging techniques
  • Ophthalmology
  • Precision medicine
  • Robotic surgery
  • Virtual reality simulation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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