Precision medicine in COPD: Where are we and where do we need to go?

Venkataramana K. Sidhaye, Kristine Nishida, Fernando J. Martinez

Research output: Contribution to journalArticlepeer-review

Abstract

Chronic obstructive pulmonary disease (COPD) was the fourth leading cause of death worldwide in 2015. Current treatments for patients ease discomfort and help decrease disease progression; however, none improve lung function or change mortality. COPD is heterogeneous in its molecular and clinical presentation, making it difficult to understand disease aetiology and define robust therapeutic strategies. Given the complexity of the disease we propose a precision medicine approach to understanding and better treating COPD. It is possible that multiOMICs can be used as a tool to integrate data from multiple fields. Moreover, analysis of electronic medical records could aid in the treatment of patients and in the predictions of outcomes. The Precision Medicine Initiative created in 2015 has made precision medicine approaches to treat disease a reality; one of these diseases being COPD.

Original languageEnglish (US)
JournalEuropean Respiratory Review
Volume27
Issue number149
DOIs
StatePublished - Sep 30 2018

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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