Precision bone and muscle loss measurements by advanced, multiple projection DEXA (AMPDXA) techniques for spaceflight applications

Harry K. Charles; Thomas J. Beck; Howard S. Feldmesser; Thomas C. Magee; Thomas S. Spisz; Vincent L. Pisacane

doi:10.1016/S0094-5765(01)00119-9

Precision bone and muscle loss measurements by advanced, multiple projection DEXA (AMPDXA) techniques for spaceflight applications

Harry K. Charles, Thomas J. Beck, Howard S. Feldmesser, Thomas C. Magee, Thomas S. Spisz, Vincent L. Pisacane

School of Medicine

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

An advanced, multiple projection, dual energy x-ray absorptiometry (AMPDXA) scanner system is under development. The AMPDXA is designed to make precision bone and muscle loss measurements necessary to determine the deleterious effects of microgravity on astronauts as well as develop countermeasures to stem their bone and muscle loss. To date, a full size test system has been developed to verify principles and the results of computer simulations. Results indicate that accurate predictions of bone mechanical properties can be determined from as few as three projections, while more projections are needed for a complete, three-dimensional reconstruction.

Original language	English (US)
Pages (from-to)	447-450
Number of pages	4
Journal	Acta Astronautica
Volume	49
Issue number	3-10
DOIs	https://doi.org/10.1016/S0094-5765(01)00119-9
State	Published - Aug 11 2001

ASJC Scopus subject areas

Aerospace Engineering

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abstract = "An advanced, multiple projection, dual energy x-ray absorptiometry (AMPDXA) scanner system is under development. The AMPDXA is designed to make precision bone and muscle loss measurements necessary to determine the deleterious effects of microgravity on astronauts as well as develop countermeasures to stem their bone and muscle loss. To date, a full size test system has been developed to verify principles and the results of computer simulations. Results indicate that accurate predictions of bone mechanical properties can be determined from as few as three projections, while more projections are needed for a complete, three-dimensional reconstruction.",

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AU - Spisz, Thomas S.

AU - Pisacane, Vincent L.

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AB - An advanced, multiple projection, dual energy x-ray absorptiometry (AMPDXA) scanner system is under development. The AMPDXA is designed to make precision bone and muscle loss measurements necessary to determine the deleterious effects of microgravity on astronauts as well as develop countermeasures to stem their bone and muscle loss. To date, a full size test system has been developed to verify principles and the results of computer simulations. Results indicate that accurate predictions of bone mechanical properties can be determined from as few as three projections, while more projections are needed for a complete, three-dimensional reconstruction.

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Precision bone and muscle loss measurements by advanced, multiple projection DEXA (AMPDXA) techniques for spaceflight applications

Abstract

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