Precision and accuracy of an artificial anterior chamber system in obtaining corneal lenticules for lamellar keratoplasty

Ashley Behrens, Arlene M.T. Dolorico, David T. Kara, Lee H. Novick, Peter J. McDonnell, Lawrence C. Chao, Sarah R. Wellik, Roy S. Chuck

Research output: Contribution to journalArticle


Purpose: To determine the precision and accuracy of an artificial anterior chamber and a manual microkeratome in obtaining corneal lenticules for lamellar keratoplasty. Setting: Department of Ophthalmology, Cornea, External Diseases and Refractive Surgery Service, University of California Irvine, Irvine, California, USA. Methods: A lamellar keratectomy was performed in 47 human corneoscleral rims. Three lenticule thicknesses (180, 300, and 360 μm heads) and 3 diameters (7.0, 8.0, and 9.0 mm) were attempted. Diameters and thicknesses were measured by planimetry and pachymetry, respectively. Results: Peripheral lenticule thickness was more likely to be within ±50 μm of the intended depth in thinner cuts (180 μm, 9/15 corneas, 60%; 300 μm, 6/16 corneas, 40%; 360 μm, 3/12 corneas, 33.3%) (P = .045). Eighty percent (32/40 corneas) were within ± 0.5 mm of the expected diameter. Accuracy was best in the 8.0 mm group, with 47.1% (8/17 corneas) within ± 0.2 mm of the expected diameter. A thickness/diameter correlation was not observed (rs ≤ 0.28). Conclusions: The precision and accuracy of this system varied according to the attempted thickness and diameter.

Original languageEnglish (US)
Pages (from-to)1679-1687
Number of pages9
JournalJournal of cataract and refractive surgery
Issue number10
StatePublished - Nov 12 2001
Externally publishedYes


ASJC Scopus subject areas

  • Surgery
  • Ophthalmology
  • Sensory Systems

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