Precise estimation of the numbers of chronic carriers of salmonella typhi in santiago, chile, an endemic area

Myron M. Levine, Robert E. Black, Claudio Lanata

Research output: Contribution to journalArticlepeer-review

131 Scopus citations

Abstract

As part of a program to control endemic typhoid fever in Santiago, Chile, an assessment was made of the magnitude of the reservoir of chronic carriers of Salmonella typhi. The availability of an accurate census and reliable data on the prevalence of biliary disease and of S. typhi carriage among persons with cholecystitis allowed an unusually precise estimate of the number of carriers. In 1980 there existed 25,019 female and 4,575 male carriers in a population of 4,264,514, yielding a crude prevalence of 694 carriers per 10' population. Because of the magnitude of this human reservoir, which includes many females of <40 years of age, it is recommended that a typhoid control program include the identification of carriers followed by health education and therapeutic interventions.

Original languageEnglish (US)
Pages (from-to)724-726
Number of pages3
JournalJournal of Infectious Diseases
Volume146
Issue number6
DOIs
StatePublished - Dec 1982
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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