TY - JOUR
T1 - Pre-menopausal and post-menopausal depressed women
AU - Roy, Alec
AU - Linnoila, Markku
AU - Jimerson, David C.
AU - Gold, Philip
AU - Pickar, David
PY - 1986
Y1 - 1986
N2 - In a consecutive series of 28 depressed women, pre-menopausal (n = 13) and post-menopausal (n = 15) patients were compared. Post-menopausal women had significantly higher levels of plasma norepinephrine, plasma 3-methoxy-4-hydroxyphenylglycol, post-dexamethasone plasma cortisol, cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol and corticotropin-releasing hormone. However, when biologic measures were adjusted for age by analyses of covariance there were no significant differences. Pre-menopausal women had had significantly more life events before the onset of depression than post-menopausal women. The implications of these findings are discussed.
AB - In a consecutive series of 28 depressed women, pre-menopausal (n = 13) and post-menopausal (n = 15) patients were compared. Post-menopausal women had significantly higher levels of plasma norepinephrine, plasma 3-methoxy-4-hydroxyphenylglycol, post-dexamethasone plasma cortisol, cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol and corticotropin-releasing hormone. However, when biologic measures were adjusted for age by analyses of covariance there were no significant differences. Pre-menopausal women had had significantly more life events before the onset of depression than post-menopausal women. The implications of these findings are discussed.
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U2 - 10.3109/00048678609158899
DO - 10.3109/00048678609158899
M3 - Article
C2 - 3494443
AN - SCOPUS:84907035770
SN - 1039-8562
VL - 20
SP - 464
EP - 469
JO - Australasian Psychiatry
JF - Australasian Psychiatry
IS - 4
ER -