Pre-menopausal and post-menopausal depressed women

Alec Roy, Markku Linnoila, David C. Jimerson, Philip Gold, David Pickar

Research output: Contribution to journalArticle

Abstract

In a consecutive series of 28 depressed women, pre-menopausal (n = 13) and post-menopausal (n = 15) patients were compared. Post-menopausal women had significantly higher levels of plasma norepinephrine, plasma 3-methoxy-4-hydroxyphenylglycol, post-dexamethasone plasma cortisol, cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol and corticotropin-releasing hormone. However, when biologic measures were adjusted for age by analyses of covariance there were no significant differences. Pre-menopausal women had had significantly more life events before the onset of depression than post-menopausal women. The implications of these findings are discussed.

Original languageEnglish (US)
Pages (from-to)464-469
Number of pages6
JournalAustralasian Psychiatry
Volume20
Issue number4
DOIs
StatePublished - 1986
Externally publishedYes

Fingerprint

Corticotropin-Releasing Hormone
Dexamethasone
Cerebrospinal Fluid
Hydrocortisone
Norepinephrine
4-hydroxyphenethylene glycol

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Roy, A., Linnoila, M., Jimerson, D. C., Gold, P., & Pickar, D. (1986). Pre-menopausal and post-menopausal depressed women. Australasian Psychiatry, 20(4), 464-469. https://doi.org/10.3109/00048678609158899

Pre-menopausal and post-menopausal depressed women. / Roy, Alec; Linnoila, Markku; Jimerson, David C.; Gold, Philip; Pickar, David.

In: Australasian Psychiatry, Vol. 20, No. 4, 1986, p. 464-469.

Research output: Contribution to journalArticle

Roy, A, Linnoila, M, Jimerson, DC, Gold, P & Pickar, D 1986, 'Pre-menopausal and post-menopausal depressed women', Australasian Psychiatry, vol. 20, no. 4, pp. 464-469. https://doi.org/10.3109/00048678609158899
Roy, Alec ; Linnoila, Markku ; Jimerson, David C. ; Gold, Philip ; Pickar, David. / Pre-menopausal and post-menopausal depressed women. In: Australasian Psychiatry. 1986 ; Vol. 20, No. 4. pp. 464-469.
@article{caa9c3bc9b1e4712864123a534df9a81,
title = "Pre-menopausal and post-menopausal depressed women",
abstract = "In a consecutive series of 28 depressed women, pre-menopausal (n = 13) and post-menopausal (n = 15) patients were compared. Post-menopausal women had significantly higher levels of plasma norepinephrine, plasma 3-methoxy-4-hydroxyphenylglycol, post-dexamethasone plasma cortisol, cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol and corticotropin-releasing hormone. However, when biologic measures were adjusted for age by analyses of covariance there were no significant differences. Pre-menopausal women had had significantly more life events before the onset of depression than post-menopausal women. The implications of these findings are discussed.",
author = "Alec Roy and Markku Linnoila and Jimerson, {David C.} and Philip Gold and David Pickar",
year = "1986",
doi = "10.3109/00048678609158899",
language = "English (US)",
volume = "20",
pages = "464--469",
journal = "Australasian Psychiatry",
issn = "1039-8562",
publisher = "Informa Healthcare",
number = "4",

}

TY - JOUR

T1 - Pre-menopausal and post-menopausal depressed women

AU - Roy, Alec

AU - Linnoila, Markku

AU - Jimerson, David C.

AU - Gold, Philip

AU - Pickar, David

PY - 1986

Y1 - 1986

N2 - In a consecutive series of 28 depressed women, pre-menopausal (n = 13) and post-menopausal (n = 15) patients were compared. Post-menopausal women had significantly higher levels of plasma norepinephrine, plasma 3-methoxy-4-hydroxyphenylglycol, post-dexamethasone plasma cortisol, cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol and corticotropin-releasing hormone. However, when biologic measures were adjusted for age by analyses of covariance there were no significant differences. Pre-menopausal women had had significantly more life events before the onset of depression than post-menopausal women. The implications of these findings are discussed.

AB - In a consecutive series of 28 depressed women, pre-menopausal (n = 13) and post-menopausal (n = 15) patients were compared. Post-menopausal women had significantly higher levels of plasma norepinephrine, plasma 3-methoxy-4-hydroxyphenylglycol, post-dexamethasone plasma cortisol, cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol and corticotropin-releasing hormone. However, when biologic measures were adjusted for age by analyses of covariance there were no significant differences. Pre-menopausal women had had significantly more life events before the onset of depression than post-menopausal women. The implications of these findings are discussed.

UR - http://www.scopus.com/inward/record.url?scp=84907035770&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84907035770&partnerID=8YFLogxK

U2 - 10.3109/00048678609158899

DO - 10.3109/00048678609158899

M3 - Article

VL - 20

SP - 464

EP - 469

JO - Australasian Psychiatry

JF - Australasian Psychiatry

SN - 1039-8562

IS - 4

ER -