Pre-Clinical MRI-Guided Focused Ultrasound: A Review of Systems and Current Practices

Nicholas Ellens, Ari Partanen

Research output: Contribution to journalReview article

Abstract

Effective pre-clinical research is a vital component in the development of MRI-guided focused ultrasound (MRgFUS) and its translation to clinic. In this review we seek to outline the challenges at hand for effective pre-clinical research, survey different solutions, and underline best practices. Furthermore, we summarize efforts to build and characterize dedicated pre-clinical MRgFUS equipment, including lab prototypes and available commercial products. Finally, we discuss constraints and considerations specific to using clinical MRgFUS equipment in preclinical research. Specifically, we examine additional hardware that has been used to adapt clinical MRgFUS equipment to better position, constrain, and image pre-clinical subjects, as well as software solutions that have been used to extend the potential and capabilities of clinical devices.

Original languageEnglish (US)
Article number7565574
JournalIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
VolumePP
Issue number99
DOIs
StatePublished - 2016

Fingerprint

Magnetic resonance imaging
Ultrasonics
hardware
prototypes
computer programs
products
Hardware

ASJC Scopus subject areas

  • Instrumentation
  • Acoustics and Ultrasonics
  • Electrical and Electronic Engineering

Cite this

Pre-Clinical MRI-Guided Focused Ultrasound : A Review of Systems and Current Practices. / Ellens, Nicholas; Partanen, Ari.

In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Vol. PP, No. 99, 7565574, 2016.

Research output: Contribution to journalReview article

@article{76ec3eda016845448751b1fd84ebf7a6,
title = "Pre-Clinical MRI-Guided Focused Ultrasound: A Review of Systems and Current Practices",
abstract = "Effective pre-clinical research is a vital component in the development of MRI-guided focused ultrasound (MRgFUS) and its translation to clinic. In this review we seek to outline the challenges at hand for effective pre-clinical research, survey different solutions, and underline best practices. Furthermore, we summarize efforts to build and characterize dedicated pre-clinical MRgFUS equipment, including lab prototypes and available commercial products. Finally, we discuss constraints and considerations specific to using clinical MRgFUS equipment in preclinical research. Specifically, we examine additional hardware that has been used to adapt clinical MRgFUS equipment to better position, constrain, and image pre-clinical subjects, as well as software solutions that have been used to extend the potential and capabilities of clinical devices.",
author = "Nicholas Ellens and Ari Partanen",
year = "2016",
doi = "10.1109/TUFFC.2016.2609238",
language = "English (US)",
volume = "PP",
journal = "IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control",
issn = "0885-3010",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
number = "99",

}

TY - JOUR

T1 - Pre-Clinical MRI-Guided Focused Ultrasound

T2 - A Review of Systems and Current Practices

AU - Ellens, Nicholas

AU - Partanen, Ari

PY - 2016

Y1 - 2016

N2 - Effective pre-clinical research is a vital component in the development of MRI-guided focused ultrasound (MRgFUS) and its translation to clinic. In this review we seek to outline the challenges at hand for effective pre-clinical research, survey different solutions, and underline best practices. Furthermore, we summarize efforts to build and characterize dedicated pre-clinical MRgFUS equipment, including lab prototypes and available commercial products. Finally, we discuss constraints and considerations specific to using clinical MRgFUS equipment in preclinical research. Specifically, we examine additional hardware that has been used to adapt clinical MRgFUS equipment to better position, constrain, and image pre-clinical subjects, as well as software solutions that have been used to extend the potential and capabilities of clinical devices.

AB - Effective pre-clinical research is a vital component in the development of MRI-guided focused ultrasound (MRgFUS) and its translation to clinic. In this review we seek to outline the challenges at hand for effective pre-clinical research, survey different solutions, and underline best practices. Furthermore, we summarize efforts to build and characterize dedicated pre-clinical MRgFUS equipment, including lab prototypes and available commercial products. Finally, we discuss constraints and considerations specific to using clinical MRgFUS equipment in preclinical research. Specifically, we examine additional hardware that has been used to adapt clinical MRgFUS equipment to better position, constrain, and image pre-clinical subjects, as well as software solutions that have been used to extend the potential and capabilities of clinical devices.

UR - http://www.scopus.com/inward/record.url?scp=85029205807&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85029205807&partnerID=8YFLogxK

U2 - 10.1109/TUFFC.2016.2609238

DO - 10.1109/TUFFC.2016.2609238

M3 - Review article

AN - SCOPUS:85027465671

VL - PP

JO - IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control

JF - IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control

SN - 0885-3010

IS - 99

M1 - 7565574

ER -