Pre- and post-dexamethasone plasma ACTH levels in depressed patients and normal controls

Alec Roy, Philip Gold, David Pickar, Owen M. Wolkowitz, George Chrousos, Steven M. Paul

Research output: Contribution to journalArticle


Levels of plasma ACTH in relation to dexamethasone administration were evaluated in 16 medication-free patients with a major depressive episode and 39 normal controls. Depressed patients had significantly higher levels of plasma ACTH than controls both at 4:00 p.m. predexamethasone and 4:00 p.m. postdexamethasone. The significance of this finding is discussed.

Original languageEnglish (US)
Pages (from-to)95-99
Number of pages5
JournalJournal of Affective Disorders
Issue number2
StatePublished - 1986
Externally publishedYes



  • Depression
  • Dexamethasone
  • Plasma ACTH

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Behavioral Neuroscience
  • Biological Psychiatry
  • Neurology
  • Psychology(all)

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