Pre- and post-dexamethasone plasma ACTH levels in depressed patients and normal controls

Alec Roy, Philip Gold, David Pickar, Owen M. Wolkowitz, George Chrousos, Steven M. Paul

Research output: Contribution to journalArticle

Abstract

Levels of plasma ACTH in relation to dexamethasone administration were evaluated in 16 medication-free patients with a major depressive episode and 39 normal controls. Depressed patients had significantly higher levels of plasma ACTH than controls both at 4:00 p.m. predexamethasone and 4:00 p.m. postdexamethasone. The significance of this finding is discussed.

Original languageEnglish (US)
Pages (from-to)95-99
Number of pages5
JournalJournal of Affective Disorders
Volume10
Issue number2
DOIs
StatePublished - 1986
Externally publishedYes

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Adrenocorticotropic Hormone
Dexamethasone

Keywords

  • Depression
  • Dexamethasone
  • Plasma ACTH

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Behavioral Neuroscience
  • Biological Psychiatry
  • Neurology
  • Psychology(all)

Cite this

Pre- and post-dexamethasone plasma ACTH levels in depressed patients and normal controls. / Roy, Alec; Gold, Philip; Pickar, David; Wolkowitz, Owen M.; Chrousos, George; Paul, Steven M.

In: Journal of Affective Disorders, Vol. 10, No. 2, 1986, p. 95-99.

Research output: Contribution to journalArticle

Roy, Alec ; Gold, Philip ; Pickar, David ; Wolkowitz, Owen M. ; Chrousos, George ; Paul, Steven M. / Pre- and post-dexamethasone plasma ACTH levels in depressed patients and normal controls. In: Journal of Affective Disorders. 1986 ; Vol. 10, No. 2. pp. 95-99.
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