Practically feasible histogram-mode and list-mode EM reconstructions with full motion compensation

Arman Rahmim, Peter Bloomfield, Sylvain Houle, Mark Lenox, Christian Michel, Vesna Sossi

Research output: Contribution to journalConference articlepeer-review

Abstract

With continuous improvements in spatial resolution of PET scanners, small patient movements during PET imaging become a significant source of resolution degradation. This work explores incorporation of motion information into EM reconstruction algorithms. Pre-correction of the data for attenuation and normalization as well as weighted schemes, in which these correction factors are incorporated into the system matrix, are considered. An important issue addressed is the existence of LORs corresponding to no actual pairs of detectors and their motion-induced "interaction" with the detectable LORs. An example of this is a scanner design with gaps existing in-between the detector heads. It is shown that to properly account for such LORs in histogram-mode and list-mode EM reconstructions, in addition to motion-correction of the data, the algorithms themselves must be modified. This modification is implemented by including time-weighted sensitivity correction factors. A practically feasible method for calculation of sensitivity factors is derived based on image-space monitoring of voxel motion during the scan.

Original languageEnglish (US)
Article numberM10-214
Pages (from-to)2589-2593
Number of pages5
JournalIEEE Nuclear Science Symposium Conference Record
Volume4
StatePublished - 2003
Event2003 IEEE Nuclear Science Symposium Conference Record - Nuclear Science Symposium, Medical Imaging Conference - Portland, OR, United States
Duration: Oct 19 2003Oct 25 2003

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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