TY - JOUR
T1 - Précis of Vigor
T2 - Neuroeconomics of Movement Control
AU - Shadmehr, Reza
AU - Ahmed, Alaa A.
N1 - Funding Information:
Financial support. This study was supported by the Japan Agency for Medical Research and Development (Brain/MINDS, grant number 19dm0207070s0101; Brain/MINDS Beyond, grant number 19dm0307003h0002); and Japan Society for the Promotion of Science (KAKENHI grant numbers 19H03536 and 18H04960).
Funding Information:
Funding statement. This study was supported by INAIL (PR19-PAS-P1 – iHannes).
Funding Information:
Financial support. JMM is supported by the Wellcome Trust Grant (104908/Z/14/Z/). This research received no further specific grant from any funding agency, commercial, or not-for-profit sectors.
Funding Information:
Financial support. This study was supported by the Deutsche Forschungsgemeinschaft (MR, grant number RO3579/12-1), (SO, grant number OH274/2-2), and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (MR, Grant agreement number 865715).
Funding Information:
D.T. is funded by an ATIP/Avenir (Inserm/CNRS) grant.
Funding Information:
Financial support. This study was supported by grants from the Office of Naval Research (N00014-15-1-2312), the National Institutes of Health (R01-NS078311 and R01-NS096083), and the National Science Foundation (CNS-1714623).
Funding Information:
Financial support. T.M. is supported by Kakenhi from Japan Society for Promotion of Science (JSPS); Grant-in-aid for scientific research (C) JP18K07351 and Promotion of Joint International Research (B) JP19KK0211. A.K. is supported by JSPS Kakenhi; Grant-in-Aid for JSPS Fellows JP19J40208 and Grant-in-Aid for Challenging Research (Exploratory) JP17K18718. Y.O. is supported by JSPS Kakenhi; Grant-in-Aid for Early-Career Scientists JP18K13267.
Funding Information:
Financial support. This study was supported by the Brazilian Council of Science and Technology (CNPq), grant number 306323/2019-2.
Publisher Copyright:
Copyright © The Author(s), 2020. Published by Cambridge University Press.
PY - 2021/12/2
Y1 - 2021/12/2
N2 - Why do we run toward people we love, but only walk toward others? Why do people in New York seem to walk faster than other cities? Why do our eyes linger longer on things we value more? There is a link between how the brain assigns value to things, and how it controls our movements. This link is an ancient one, developed through shared neural circuits that on one hand teach us how to value things, and on the other hand control the vigor with which we move. As a result, when there is damage to systems that signal reward, like dopamine and serotonin, that damage not only affects our mood and patterns of decision-making, but how we move. In this book, we first ask why, in principle, evolution should have developed a shared system of control between valuation and vigor. We then focus on the neural basis of vigor, synthesizing results from experiments that have measured activity in various brain structures and neuromodulators, during tasks in which animals decide how patiently they should wait for reward, and how vigorously they should move to acquire it. Thus, the way we move unmasks one of our well-guarded secrets: how much we value the thing we are moving toward.
AB - Why do we run toward people we love, but only walk toward others? Why do people in New York seem to walk faster than other cities? Why do our eyes linger longer on things we value more? There is a link between how the brain assigns value to things, and how it controls our movements. This link is an ancient one, developed through shared neural circuits that on one hand teach us how to value things, and on the other hand control the vigor with which we move. As a result, when there is damage to systems that signal reward, like dopamine and serotonin, that damage not only affects our mood and patterns of decision-making, but how we move. In this book, we first ask why, in principle, evolution should have developed a shared system of control between valuation and vigor. We then focus on the neural basis of vigor, synthesizing results from experiments that have measured activity in various brain structures and neuromodulators, during tasks in which animals decide how patiently they should wait for reward, and how vigorously they should move to acquire it. Thus, the way we move unmasks one of our well-guarded secrets: how much we value the thing we are moving toward.
KW - basal ganglia
KW - decision-making
KW - dopamine
KW - motor control
KW - neuroeconomics
KW - serotonin
UR - http://www.scopus.com/inward/record.url?scp=85097827873&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85097827873&partnerID=8YFLogxK
U2 - 10.1017/S0140525X20000667
DO - 10.1017/S0140525X20000667
M3 - Article
C2 - 33261698
AN - SCOPUS:85097827873
VL - 44
SP - 191
EP - 204
JO - Behavioral and Brain Sciences
JF - Behavioral and Brain Sciences
SN - 0140-525X
ER -