TY - JOUR
T1 - Power spectral analysis of EEG activity during sleep in cigarette smokers
AU - Zhang, Lin
AU - Samet, Jonathan
AU - Caffo, Brian
AU - Bankman, Isaac
AU - Punjabi, Naresh M.
N1 - Funding Information:
Supported by the National Heart, Lung, and Blood Institute through the following cooperative agreements: HL53940 (University of Washington); HL53941 (Boston University); HL63463 (Case Western Reserve University); HL53937 (Johns Hopkins University); HL53938 (University of Arizona); HL53916 (University of California, Davis); HL53934 (University of Minnesota); HL63429 (Missouri Breaks Research); and HL53931 (New York University). Dr. Punjabi was also supported by grants HL075078, HL086862, and AG025553.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2008/2
Y1 - 2008/2
N2 - Background: Research on the effects of cigarette smoking on sleep architecture is limited. The objective of this investigation was to examine differences in sleep EEG between smokers and nonsmokers. Methods: Smokers and nonsmokers who were free of all medical comorbidities were matched on different factors, including age, gender, race, body mass index, and anthropometric measures. Home polysomnography was conducted using a standard recording montage. Sleep architecture was assessed using visual sleep-stage scoring. The discrete fast Fourier transform was used to calculate the EEG power spectrum for the entire night within contiguous 30-s epochs of sleep for the following frequency bandwidths: δ (0.8 to 4.0 Hz); θ (4.1 to 8.0 Hz); α (8.1 to 13.0 Hz); and β (13.1 to 20.0 Hz). Results: Conventional sleep stages were similar between the two groups. However, spectral analysis of the sleep EEG showed that, compared to nonsmokers, smokers had a lower percentage of EEG power in the δ-bandwidth (59.7% vs 62.6%, respectively; p < 0.04) and higher percentage of EEG power in α-bandwidth (15.6% vs 12.5%, respectively; p < 0.001). Differences in the EEG power spectrum between smokers and nonsmokers were greatest in the early part of the sleep period and decreased toward the end. Subjective complaints of lack of restful sleep were also more prevalent in smokers than in nonsmokers (22.5% vs 5.0%, respectively; p < 0.02) and were explained, in part, by the differences in EEG spectral power. Conclusions: Cigarette smokers manifest disturbances in the sleep EEG that are not evident in conventional measures of sleep architecture. Nicotine in cigarette smoke and withdrawal from it during sleep may contribute to these changes and the subjective experience of nonrestorative sleep.
AB - Background: Research on the effects of cigarette smoking on sleep architecture is limited. The objective of this investigation was to examine differences in sleep EEG between smokers and nonsmokers. Methods: Smokers and nonsmokers who were free of all medical comorbidities were matched on different factors, including age, gender, race, body mass index, and anthropometric measures. Home polysomnography was conducted using a standard recording montage. Sleep architecture was assessed using visual sleep-stage scoring. The discrete fast Fourier transform was used to calculate the EEG power spectrum for the entire night within contiguous 30-s epochs of sleep for the following frequency bandwidths: δ (0.8 to 4.0 Hz); θ (4.1 to 8.0 Hz); α (8.1 to 13.0 Hz); and β (13.1 to 20.0 Hz). Results: Conventional sleep stages were similar between the two groups. However, spectral analysis of the sleep EEG showed that, compared to nonsmokers, smokers had a lower percentage of EEG power in the δ-bandwidth (59.7% vs 62.6%, respectively; p < 0.04) and higher percentage of EEG power in α-bandwidth (15.6% vs 12.5%, respectively; p < 0.001). Differences in the EEG power spectrum between smokers and nonsmokers were greatest in the early part of the sleep period and decreased toward the end. Subjective complaints of lack of restful sleep were also more prevalent in smokers than in nonsmokers (22.5% vs 5.0%, respectively; p < 0.02) and were explained, in part, by the differences in EEG spectral power. Conclusions: Cigarette smokers manifest disturbances in the sleep EEG that are not evident in conventional measures of sleep architecture. Nicotine in cigarette smoke and withdrawal from it during sleep may contribute to these changes and the subjective experience of nonrestorative sleep.
KW - Cigarette smoking
KW - Power spectral analysis
KW - Sleep architecture
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U2 - 10.1378/chest.07-1190
DO - 10.1378/chest.07-1190
M3 - Article
C2 - 17925420
AN - SCOPUS:39449139631
VL - 133
SP - 427
EP - 432
JO - Chest
JF - Chest
SN - 0012-3692
IS - 2
ER -