Abstract
We consider the power and sample size calculation of diagnostic studies with normally distributed multiple correlated test results. We derive test statistics and obtain power and sample size formulas. The methods are illustrated using an example of comparison of CT and PET scanner for detecting extra-hepatic disease for colorectal cancer.
Original language | English (US) |
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Pages (from-to) | 140-150 |
Number of pages | 11 |
Journal | Biometrical Journal |
Volume | 47 |
Issue number | 2 |
DOIs | |
State | Published - Apr 2005 |
Externally published | Yes |
Keywords
- Area under a curve
- Correlated measurements
- Power and sample size
- Receiver operating characteristic curves
ASJC Scopus subject areas
- Statistics and Probability
- Statistics, Probability and Uncertainty