Power and sample size calculation of comparative diagnostic accuracy studies with multiple correlated test results

Aiyi Liu, Enrique F. Schisterman, Madhu Mazumdar, Jiang Hu

Research output: Contribution to journalArticle

Abstract

We consider the power and sample size calculation of diagnostic studies with normally distributed multiple correlated test results. We derive test statistics and obtain power and sample size formulas. The methods are illustrated using an example of comparison of CT and PET scanner for detecting extra-hepatic disease for colorectal cancer.

Original languageEnglish (US)
Pages (from-to)140-150
Number of pages11
JournalBiometrical Journal
Volume47
Issue number2
DOIs
StatePublished - Apr 2005
Externally publishedYes

Keywords

  • Area under a curve
  • Correlated measurements
  • Power and sample size
  • Receiver operating characteristic curves

ASJC Scopus subject areas

  • Statistics and Probability

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