TY - JOUR
T1 - Potential Influence of Olfactory, Gustatory, and Pharyngolaryngeal Sensory Dysfunctions on Swallowing Physiology in COVID-19
AU - Vergara, José
AU - Lirani-Silva, Camila
AU - Brodsky, Martin B.
AU - Miles, Anna
AU - Clavé, Pere
AU - Nascimento, Weslania
AU - Mourão, Lúcia Figueiredo
N1 - Publisher Copyright:
© American Academy of Otolaryngology–Head and Neck Surgery Foundation 2020.
PY - 2021/6
Y1 - 2021/6
N2 - Persistent smell and taste disorders have been reported as some of the most common symptoms after COVID-19 (coronavirus disease 2019). Sensory, olfactory, and gustatory functions perform an important role in the initiation and modulation of oropharyngeal swallow biomechanics and salivation as well as in mealtime enjoyment and appetite. Yet, the details of this interaction remain relatively unknown in patients who are infected with and recovering from COVID-19. In this commentary, we discuss the possible impacts of SARS-CoV-2 on the central and peripheral nervous system and consider the pathophysiology of olfactory, gustatory, and pharyngolaryngeal sensory deficits and its influence on deglutition, describing hypotheses and offering guidance for future research.
AB - Persistent smell and taste disorders have been reported as some of the most common symptoms after COVID-19 (coronavirus disease 2019). Sensory, olfactory, and gustatory functions perform an important role in the initiation and modulation of oropharyngeal swallow biomechanics and salivation as well as in mealtime enjoyment and appetite. Yet, the details of this interaction remain relatively unknown in patients who are infected with and recovering from COVID-19. In this commentary, we discuss the possible impacts of SARS-CoV-2 on the central and peripheral nervous system and consider the pathophysiology of olfactory, gustatory, and pharyngolaryngeal sensory deficits and its influence on deglutition, describing hypotheses and offering guidance for future research.
KW - COVID-19
KW - SARS-CoV-2
KW - deglutition disorders
KW - sensory
KW - smell
KW - taste
UR - http://www.scopus.com/inward/record.url?scp=85095823345&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85095823345&partnerID=8YFLogxK
U2 - 10.1177/0194599820972680
DO - 10.1177/0194599820972680
M3 - Comment/debate
C2 - 33167752
AN - SCOPUS:85095823345
SN - 0194-5998
VL - 164
SP - 1134
EP - 1135
JO - Otolaryngology - Head and Neck Surgery (United States)
JF - Otolaryngology - Head and Neck Surgery (United States)
IS - 6
ER -