Potential for ultrafast protein separations with capillary-channeled polymer (C-CP) fiber columns

Dwella M. Nelson, R. Kenneth Marcus

Research output: Contribution to journalArticle

Abstract

Capillary-channeled polymer (C-CP) fibers are demonstrated as a potential stationary phase for liquid chromatography separation of protein mixtures. Separation of a synthetic mixture of four proteins is accomplished within a 45-second window using a conventional revered-phase (RP) gradient, at a mobile phase flow rate of 7 mL/min (10,200 mm/min).

Original languageEnglish (US)
Pages (from-to)95-99
Number of pages5
JournalProtein and Peptide Letters
Volume13
Issue number1
DOIs
StatePublished - Jan 1 2006
Externally publishedYes

Keywords

  • Capillary-channeled polymers
  • Fibers
  • Liquid chromatography
  • Proteins
  • Ultrafast separation

ASJC Scopus subject areas

  • Structural Biology
  • Biochemistry

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