Potential for immune reconstitution through G-CSF treatment of HIV patients

Sonja Von Aulock, Thomas Hartung

Research output: Contribution to journalReview articlepeer-review

Abstract

New treatment strategies for HIV/AIDS are very successful in reducing viral load. However, reconstitution of the immune system takes about one year and may be insufficient or remain incomplete. During this time the patient remains prone to opportunistic infections as a result of the complex immune dysfunction caused by the virus. Recombinant granulocyte colony-stimulating factor (G-CSF) has diverse immunomodulatory properties which may be beneficial in aiding immune reconstitution.

Original languageEnglish (US)
Pages (from-to)111-120
Number of pages10
JournalArchivum Immunologiae et Therapiae Experimentalis
Volume50
Issue number2
StatePublished - Jun 11 2002
Externally publishedYes

Keywords

  • AIDS
  • G-CSF
  • HIV
  • Immune reconstitution

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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