Potential contribution of maternal zinc supplementation during pregnancy to maternal and child survival

Laura Caulfield, Nelly Zavaleta, Anuraj H. Shankar, Mario Merialdi

Research output: Contribution to journalArticle

Abstract

Mild-to-moderate zinc deficiency may be relatively common worldwide, but the public health importance of this degree of zinc deficiency is not well defined. The purpose of this review was to provide a conceptual framework for evaluating the public health importance of maternal zinc deficiency as it relates to fetal growth and development, complications of pregnancy, labor and delivery, and maternal and infant health. The mechanisms through which zinc deficiency could influence health outcomes are well described. The results of experimental studies conducted in animal models have motivated concern about the potential health effects of mild-to-moderate maternal zinc deficiency. Observational studies in human populations have produced strong associations between poor maternal zinc status and various indicators of poor pregnancy outcome, but supplementation trials have not produced strong, or even consistent results. Supplementation trials are needed to define the public health importance of maternal zinc deficiency worldwide.

Original languageEnglish (US)
JournalAmerican Journal of Clinical Nutrition
Volume68
Issue number2 SUPPL.
StatePublished - Aug 1998

Fingerprint

Zinc
zinc
Mothers
pregnancy
Pregnancy
Survival
public health
Public Health
fetal development
Fetal Development
Obstetric Labor Complications
pregnancy complications
pregnancy outcome
Pregnancy Complications
Health
observational studies
Pregnancy Outcome
Growth and Development
human population
Observational Studies

Keywords

  • Child health
  • Development
  • Immunology
  • Maternal zinc deficiency
  • Parturition
  • Pregnancy
  • Supplementation
  • Survival

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Potential contribution of maternal zinc supplementation during pregnancy to maternal and child survival. / Caulfield, Laura; Zavaleta, Nelly; Shankar, Anuraj H.; Merialdi, Mario.

In: American Journal of Clinical Nutrition, Vol. 68, No. 2 SUPPL., 08.1998.

Research output: Contribution to journalArticle

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