Potential applications of global protein expression analysis (proteomics) in morbid obesity and bariatric surgery

Gerald Brandacher, Georg Golderer, Katrin Kienzl, Ernst R. Werner, Raimund Margreiter, Helmut G. Weiss

Research output: Contribution to journalReview articlepeer-review

Abstract

Global protein expression analysis, known as proteomics, has emerged as a novel scientific technology currently successfully applied to several fields of medicine including cancer and transplantation. Thereby, a thorough exploration of the pathogenic mechanisms and a better understanding of the pathophysiology of diseases as well as identification of diagnostic biomarkers have been achieved. In this paper, we outline the basic principles and potential applications of this promising tool in bariatric surgery where proteomics might hold great potential for new insights into diagnostic and therapeutic decision making based on improved knowledge of metabolic regulations pre- and postsurgical interventions in morbidly obese patients.

Original languageEnglish (US)
Pages (from-to)905-910
Number of pages6
JournalObesity Surgery
Volume18
Issue number7
DOIs
StatePublished - Jul 2008
Externally publishedYes

Keywords

  • Bariatric surgery
  • Biomarkers
  • Metabolic regulation
  • Morbid obesity
  • Proteomics

ASJC Scopus subject areas

  • Surgery
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

Fingerprint

Dive into the research topics of 'Potential applications of global protein expression analysis (proteomics) in morbid obesity and bariatric surgery'. Together they form a unique fingerprint.

Cite this