TY - JOUR
T1 - Posttraumatic stress disorder, gender, and problem profiles in substance dependent patients
AU - Peirce, Jessica M.
AU - Kindbom, Kori A.
AU - Waesche, Matthew C.
AU - Yuscavage, Abigail S.E.
AU - Brooner, Robert K.
N1 - Funding Information:
Funding support for the study was provided by the following USPHS-NIDA research projects: K23 DA 015739 (Peirce), P50 DA 05273 (Bigelow), R01 DA 05569 (Brooner), and R01 DA 12049 (Brooner). The authors appreciate the statistical supervision and assistance given by Ken Kolodner, Sc.D. The authors also gratefully acknowledge the expertise and contribution of staff in the research assessment unit, especially: Jennifer Hahn, Ph.D.; Mary Beth Mudric, M.S.; Mark Levinson, M.A.; Jennifer Mucha, M.A.; James Blucher, M.A.; and Regina Schmidt, M.S. Portions of the data were presented as a poster at the annual meeting of the College on Problems of Drug Dependence in June 2002.
PY - 2008/4
Y1 - 2008/4
N2 - Patients with a chronic and severe substance-use disorder who also have a history of posttraumatic stress disorder (PTSD) are thought to have a unique set of problems. The present study assessed psychiatric disorders, psychosocial problems, and traumatic events with structured interviews in 747 men and 693 women enrolling in urban opioid substitution treatment programs from 1995 to 2001. Participants with versus without a history of PTSD were more likely to have a history of many other psychiatric disorders and demonstrated more current and historical medical, employment, family/social, and psychiatric problems. PTSD was generally unrelated to substance-use disorder severity or diagnoses, with the exception of an increased risk of alcohol dependence. Women were more likely than men to have experienced sexual assault, and less likely to have been physically assaulted, although these events precipitated PTSD at equivalent rates across gender. In contrast, witnessing or hearing about the death or injury of others was more likely to precipitate PTSD in women than men. Female gender, exposure to combat, sexual assault, or physical assault, and a history of major mood or anxiety disorder were the best predictors of PTSD in this group. Study limitations are noted.
AB - Patients with a chronic and severe substance-use disorder who also have a history of posttraumatic stress disorder (PTSD) are thought to have a unique set of problems. The present study assessed psychiatric disorders, psychosocial problems, and traumatic events with structured interviews in 747 men and 693 women enrolling in urban opioid substitution treatment programs from 1995 to 2001. Participants with versus without a history of PTSD were more likely to have a history of many other psychiatric disorders and demonstrated more current and historical medical, employment, family/social, and psychiatric problems. PTSD was generally unrelated to substance-use disorder severity or diagnoses, with the exception of an increased risk of alcohol dependence. Women were more likely than men to have experienced sexual assault, and less likely to have been physically assaulted, although these events precipitated PTSD at equivalent rates across gender. In contrast, witnessing or hearing about the death or injury of others was more likely to precipitate PTSD in women than men. Female gender, exposure to combat, sexual assault, or physical assault, and a history of major mood or anxiety disorder were the best predictors of PTSD in this group. Study limitations are noted.
KW - Gender
KW - PTSD
KW - Substance use disorder
KW - Trauma
KW - Treatment
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U2 - 10.1080/10826080701204623
DO - 10.1080/10826080701204623
M3 - Article
C2 - 18393079
AN - SCOPUS:41949112811
SN - 1082-6084
VL - 43
SP - 596
EP - 611
JO - Substance Use and Misuse
JF - Substance Use and Misuse
IS - 5
ER -