TY - JOUR
T1 - Postmastectomy radiation therapy and breast reconstruction
T2 - An analysis of complications and patient satisfaction
AU - Lee, Bernard T.
AU - A. Adesiyun, Tolulope
AU - Colakoglu, Salih
AU - Curtis, Michael S.
AU - Yueh, Janet H.
AU - E. Anderson, Katarina
AU - Tobias, Adam M.
AU - Recht, Abram
N1 - Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2010/5
Y1 - 2010/5
N2 - The indications for postmastectomy radiotherapy (PMRT) have expanded over the past decade. This study examines PMRT and reconstruction compared with a control group without radiotherapy. There were 919 reconstructed breasts identified (1999-2006) and separated into 3 groups: mastectomy with PMRT before reconstruction (n = 57), immediate reconstruction then PMRT (n = 59), and reconstruction without PMRT (n = 665). A validated questionnaire assessed patient satisfaction (response rate 73.7%). Overall complication rates for patients undergoing PMRT (before and after reconstruction) were higher than that of the controls (39.66% vs. 23.16%, P < 0.001). Immediate reconstruction before PMRT had increased overall and late (>90 days) complication rates, compared with controls (47.46% vs. 23.16%, P < 0.001; 33.90% vs. 15.59%, P < 0.001, respectively); however general and aesthetic satisfaction was similar. In contrast, PMRT before reconstruction has similar complication rates and general satisfaction with controls, but decreased aesthetic satisfaction (50% vs. 66.88%, P < 0.035).
AB - The indications for postmastectomy radiotherapy (PMRT) have expanded over the past decade. This study examines PMRT and reconstruction compared with a control group without radiotherapy. There were 919 reconstructed breasts identified (1999-2006) and separated into 3 groups: mastectomy with PMRT before reconstruction (n = 57), immediate reconstruction then PMRT (n = 59), and reconstruction without PMRT (n = 665). A validated questionnaire assessed patient satisfaction (response rate 73.7%). Overall complication rates for patients undergoing PMRT (before and after reconstruction) were higher than that of the controls (39.66% vs. 23.16%, P < 0.001). Immediate reconstruction before PMRT had increased overall and late (>90 days) complication rates, compared with controls (47.46% vs. 23.16%, P < 0.001; 33.90% vs. 15.59%, P < 0.001, respectively); however general and aesthetic satisfaction was similar. In contrast, PMRT before reconstruction has similar complication rates and general satisfaction with controls, but decreased aesthetic satisfaction (50% vs. 66.88%, P < 0.035).
KW - Breast cancer
KW - Breast reconstruction
KW - Mastectomy
KW - Radiation therapy
UR - http://www.scopus.com/inward/record.url?scp=77951769554&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77951769554&partnerID=8YFLogxK
U2 - 10.1097/SAP.0b013e3181db7585
DO - 10.1097/SAP.0b013e3181db7585
M3 - Article
C2 - 20395800
AN - SCOPUS:77951769554
SN - 0148-7043
VL - 64
SP - 679
EP - 683
JO - Annals of plastic surgery
JF - Annals of plastic surgery
IS - 5
ER -