Posthemorrhagic and postinflammatory complications

Joanna Y. Wang, Edward S. Ahn

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Although the incidence of intraventricular hemorrhage (IVH) and posthemorrhagic hydrocephalus (PHH) in preterm infants is decreasing, these conditions are still associated with poor neurodevelopmental and functional outcomes. Additionally, with the growing viability of infants born at younger estimated gestational ages (EGAs), these conditions remain significant burdens as IVH severity increases with prematurity. Despite improvements in neonatal care, there still lacks a uniform paradigm for the treatment and management of PHH. Patients with PHH typically are initially treated with a temporizing device that allows for these infants to develop more favorable immunologic and nutritional statuses; a permanent ventriculoperitoneal (VP) shunt is later inserted in cases of persistent ventricular dilation and symptomatic hydrocephalus. This patient population is at high risk for temporizing device and shunt complications, especially shunt obstruction and infection, slit-ventricle syndrome, and the development of loculated hydrocephalus. The impact of these complications on long-term neurodevelopmental outcomes is unclear; however, there are few alternative methods to avoid prolonged shunt dependence in these patients.

Original languageEnglish (US)
Title of host publicationComplications of CSF Shunting in Hydrocephalus
Subtitle of host publicationPrevention, Identification, and Management
PublisherSpringer International Publishing
Pages149-158
Number of pages10
ISBN (Electronic)9783319099613
ISBN (Print)9783319099606
DOIs
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • Medicine(all)

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