Postcoital penile washing and the risk of HIV acquisition in uncircumcised men

Fredrick E. Makumbi, Victor Ssempijja, Joseph Sekasanvu, Robert Ssekubugu, Godfrey Kigozi, Stephen Watya, Gertrude Nakigozi, David Serwadda, Maria Wawer, Ronald H. Gray

Research output: Contribution to journalArticle

Abstract

Background:Postcoital genital washing by uncircumcised men may affect the risk of male HIV acquisition.Method:We assessed the association between self-reported washing after sex in 2976 initially HIV-negative, uncircumcised men enrolled in a prospective cohort study in Rakai, Uganda.Results:Data from the 2976 participants who reported sexual intercourse in the past 12 months contributed 4290 visits, with 7316.6 person-years of observation during the 2-year follow-up. The overall HIV-incidence was 1.28/100 person-years 95%CI (1.04-1.57). About 91.0% of men reported washing their penis after sex, and their HIV incidence was 1.34/100 person-years (95%CI 1.08-1.66), compared with an incidence of 0.62/100 person-years (95%CI 0.17-1.60) in men who did not wash their penis after intercourse. Using Poisson multivariable regression, the adjusted incidence rate ratio of HIV acquisition associated with postcoital washing was 1.94 (95%CI 0.71-5.29).Conclusion:Postcoital penile washing, as practiced in this rural African population does not afford protection from HIV acquisition among uncircumcised men, and may increase risk.

Original languageEnglish (US)
Pages (from-to)1669-1673
Number of pages5
JournalAIDS
Volume30
Issue number10
DOIs
StatePublished - Jun 19 2016

Keywords

  • HIV incidence
  • Rakai
  • Uganda
  • postcoital washing
  • uncircumcised men

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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  • Cite this

    Makumbi, F. E., Ssempijja, V., Sekasanvu, J., Ssekubugu, R., Kigozi, G., Watya, S., Nakigozi, G., Serwadda, D., Wawer, M., & Gray, R. H. (2016). Postcoital penile washing and the risk of HIV acquisition in uncircumcised men. AIDS, 30(10), 1669-1673. https://doi.org/10.1097/QAD.0000000000001097