Postchallenge hyperglycemia and mortality in a national sample of U.S. adults

Sharon H. Saydah, Montserrat Miret, Jennifer Sung, Cristina Varas, Douglas Gause, Frederick L. Brancati

Research output: Contribution to journalArticle

Abstract

OBJECTIVE - Although postchallenge hyperglycemia is a well-established feature of type 2 diabetes, its association with risk of mortality is uncertain. Therefore, the aim of this study was to assess the independent association of fasting and 2-h glucose levels with all-cause and cardiovascular disease (CVD) mortality. RESEARCH DESIGN AND METHODS - We analyzed data from the Second National Health and Nutrition Examination Survey (NHANES II) Mortality Study, a prospective cohort study of U.S. adults examined in the NHANES II, and focused on the 3,092 adults aged 30-74 years who underwent an oral glucose tolerance test at baseline (1976-1980). Deaths were identified from U.S. national mortality files from 1976 to 1992. To account for the complex survey design, we used SUDAAN statistical software for weighted analysis. RESULTS - Compared with their normoglycemic counterparts (fasting glucose [FG]

Original languageEnglish (US)
Pages (from-to)1397-1402
Number of pages6
JournalDiabetes Care
Volume24
Issue number8
StatePublished - 2001

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Hyperglycemia
Nutrition Surveys
Mortality
Fasting
Glucose
Glucose Tolerance Test
Type 2 Diabetes Mellitus
Cohort Studies
Research Design
Cardiovascular Diseases
Software
Prospective Studies

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

Saydah, S. H., Miret, M., Sung, J., Varas, C., Gause, D., & Brancati, F. L. (2001). Postchallenge hyperglycemia and mortality in a national sample of U.S. adults. Diabetes Care, 24(8), 1397-1402.

Postchallenge hyperglycemia and mortality in a national sample of U.S. adults. / Saydah, Sharon H.; Miret, Montserrat; Sung, Jennifer; Varas, Cristina; Gause, Douglas; Brancati, Frederick L.

In: Diabetes Care, Vol. 24, No. 8, 2001, p. 1397-1402.

Research output: Contribution to journalArticle

Saydah, SH, Miret, M, Sung, J, Varas, C, Gause, D & Brancati, FL 2001, 'Postchallenge hyperglycemia and mortality in a national sample of U.S. adults', Diabetes Care, vol. 24, no. 8, pp. 1397-1402.
Saydah SH, Miret M, Sung J, Varas C, Gause D, Brancati FL. Postchallenge hyperglycemia and mortality in a national sample of U.S. adults. Diabetes Care. 2001;24(8):1397-1402.
Saydah, Sharon H. ; Miret, Montserrat ; Sung, Jennifer ; Varas, Cristina ; Gause, Douglas ; Brancati, Frederick L. / Postchallenge hyperglycemia and mortality in a national sample of U.S. adults. In: Diabetes Care. 2001 ; Vol. 24, No. 8. pp. 1397-1402.
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