Abstract
Plasma cortisol levels were studied in the cord blood and neonatal blood of the following vaginally delivered groups: (A) postmature; (B) postterm (but not postmature); and (C) term neonates. Significantly lower levels of 8 a.m. neonatal plasma cortisol were found in postmature neonates when compared with term neonates (P <0.02) or merely postterm neonates (P <0.02). No difference was found in the cord blood cortisol levels in all three groups. Contrary to the traditional belief that postmaturity results from placental aging, our findings appear to indicate that postmaturity represents a specific fetal disorder. Fetal adrenal insufficiency may be a characteristic of this disorder. Prolonged pregnancy in these cases may reflect inability of the affected fetus to initiate labor.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 366-370 |
| Number of pages | 5 |
| Journal | American Journal of Obstetrics and Gynecology |
| Volume | 121 |
| Issue number | 3 |
| State | Published - Feb 1 1975 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Medicine(all)
- Obstetrics and Gynecology
Cite this
Possible role of the fetal adrenal glands in the etiology of postmaturity. / Nwosu, Uchenna; Wallach, Edward E; Boggs, Thomas R.; Nemiroff, Richard L.; Bongiovanni, Alfred M.
In: American Journal of Obstetrics and Gynecology, Vol. 121, No. 3, 01.02.1975, p. 366-370.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Possible role of the fetal adrenal glands in the etiology of postmaturity
AU - Nwosu, Uchenna
AU - Wallach, Edward E
AU - Boggs, Thomas R.
AU - Nemiroff, Richard L.
AU - Bongiovanni, Alfred M.
PY - 1975/2/1
Y1 - 1975/2/1
N2 - Plasma cortisol levels were studied in the cord blood and neonatal blood of the following vaginally delivered groups: (A) postmature; (B) postterm (but not postmature); and (C) term neonates. Significantly lower levels of 8 a.m. neonatal plasma cortisol were found in postmature neonates when compared with term neonates (P <0.02) or merely postterm neonates (P <0.02). No difference was found in the cord blood cortisol levels in all three groups. Contrary to the traditional belief that postmaturity results from placental aging, our findings appear to indicate that postmaturity represents a specific fetal disorder. Fetal adrenal insufficiency may be a characteristic of this disorder. Prolonged pregnancy in these cases may reflect inability of the affected fetus to initiate labor.
AB - Plasma cortisol levels were studied in the cord blood and neonatal blood of the following vaginally delivered groups: (A) postmature; (B) postterm (but not postmature); and (C) term neonates. Significantly lower levels of 8 a.m. neonatal plasma cortisol were found in postmature neonates when compared with term neonates (P <0.02) or merely postterm neonates (P <0.02). No difference was found in the cord blood cortisol levels in all three groups. Contrary to the traditional belief that postmaturity results from placental aging, our findings appear to indicate that postmaturity represents a specific fetal disorder. Fetal adrenal insufficiency may be a characteristic of this disorder. Prolonged pregnancy in these cases may reflect inability of the affected fetus to initiate labor.
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M3 - Article
C2 - 1115150
AN - SCOPUS:0016439052
VL - 121
SP - 366
EP - 370
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
SN - 0002-9378
IS - 3
ER -