Possible linkage of alcoholism, monoamine oxidase activity and P300 amplitude to markers on chromosome 12q24

Suh Hang Hank Juo; Elizabeth W. Pugh; Agnes Baffoe-Bonnie; Albert Kingman; Alexa J.M. Sorant; Alison P. Klein; Jennifer O'Neill; Rasika A. Mathias; Alexander F. Wilson; Joan E. Bailey-Wilson

doi:10.1002/gepi.1370170733

Possible linkage of alcoholism, monoamine oxidase activity and P300 amplitude to markers on chromosome 12q24

Suh Hang Hank Juo, Elizabeth W. Pugh, Agnes Baffoe-Bonnie, Albert Kingman, Alexa J.M. Sorant, Alison P. Klein, Jennifer O'Neill, Rasika A. Mathias, Alexander F. Wilson, Joan E. Bailey-Wilson

School of Medicine

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Multipoint linkage analysis was used to screen for evidence of linkage between alcoholism and five alcoholism-related quantitative traits. The results suggest that a susceptibility locus that influences monoamine oxidase activity and P300 amplitude at the Pz lead, and increases the risk of alcohol dependence may be linked to markers in the 12q24 region. Furthermore, the susceptibility for alcoholism may be associated with allele 3 (allele size 144) of D12S392.

Original language	English (US)
Pages (from-to)	S193-S198
Journal	Genetic epidemiology
Volume	17
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1002/gepi.1370170733
State	Published - 1999

Keywords

Association
Genetics
MAO

ASJC Scopus subject areas

Epidemiology
Genetics(clinical)

Access to Document

10.1002/gepi.1370170733

Cite this

@article{45a1182673384e9c899c2340c8b21d0d,

title = "Possible linkage of alcoholism, monoamine oxidase activity and P300 amplitude to markers on chromosome 12q24",

abstract = "Multipoint linkage analysis was used to screen for evidence of linkage between alcoholism and five alcoholism-related quantitative traits. The results suggest that a susceptibility locus that influences monoamine oxidase activity and P300 amplitude at the Pz lead, and increases the risk of alcohol dependence may be linked to markers in the 12q24 region. Furthermore, the susceptibility for alcoholism may be associated with allele 3 (allele size 144) of D12S392.",

keywords = "Association, Genetics, MAO",

author = "Juo, {Suh Hang Hank} and Pugh, {Elizabeth W.} and Agnes Baffoe-Bonnie and Albert Kingman and Sorant, {Alexa J.M.} and Klein, {Alison P.} and Jennifer O'Neill and Mathias, {Rasika A.} and Wilson, {Alexander F.} and Bailey-Wilson, {Joan E.}",

year = "1999",

doi = "10.1002/gepi.1370170733",

language = "English (US)",

volume = "17",

pages = "S193--S198",

journal = "Genetic epidemiology",

issn = "0741-0395",

publisher = "Wiley-Liss Inc.",

number = "SUPPL. 1",

}

TY - JOUR

T1 - Possible linkage of alcoholism, monoamine oxidase activity and P300 amplitude to markers on chromosome 12q24

AU - Juo, Suh Hang Hank

AU - Pugh, Elizabeth W.

AU - Baffoe-Bonnie, Agnes

AU - Kingman, Albert

AU - Sorant, Alexa J.M.

AU - Klein, Alison P.

AU - O'Neill, Jennifer

AU - Mathias, Rasika A.

AU - Wilson, Alexander F.

AU - Bailey-Wilson, Joan E.

PY - 1999

Y1 - 1999

N2 - Multipoint linkage analysis was used to screen for evidence of linkage between alcoholism and five alcoholism-related quantitative traits. The results suggest that a susceptibility locus that influences monoamine oxidase activity and P300 amplitude at the Pz lead, and increases the risk of alcohol dependence may be linked to markers in the 12q24 region. Furthermore, the susceptibility for alcoholism may be associated with allele 3 (allele size 144) of D12S392.

AB - Multipoint linkage analysis was used to screen for evidence of linkage between alcoholism and five alcoholism-related quantitative traits. The results suggest that a susceptibility locus that influences monoamine oxidase activity and P300 amplitude at the Pz lead, and increases the risk of alcohol dependence may be linked to markers in the 12q24 region. Furthermore, the susceptibility for alcoholism may be associated with allele 3 (allele size 144) of D12S392.

KW - Association

KW - Genetics

KW - MAO

UR - http://www.scopus.com/inward/record.url?scp=13044315957&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=13044315957&partnerID=8YFLogxK

U2 - 10.1002/gepi.1370170733

DO - 10.1002/gepi.1370170733

M3 - Article

C2 - 10597435

AN - SCOPUS:13044315957

SN - 0741-0395

VL - 17

SP - S193-S198

JO - Genetic epidemiology

JF - Genetic epidemiology

IS - SUPPL. 1

ER -

Possible linkage of alcoholism, monoamine oxidase activity and P300 amplitude to markers on chromosome 12q24

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this