Abstract
Coexpression of bovine papillomavirus L1 with L2 mutants lacking either eight N-terminal or nine C-terminal amino acids that encode positively charged domains resulted in wild-type levels of viral genome encapsidation. Despite wild-type binding to the cell surface, the resulting virions were noninfectious. An L2 mutant encoding a scrambled version of the nine C-terminal residues restored infectivity, in contrast to an L2 mutant encoding a scrambled version of the N-terminal residues.
Original language | English (US) |
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Pages (from-to) | 10493-10497 |
Number of pages | 5 |
Journal | Journal of virology |
Volume | 75 |
Issue number | 21 |
DOIs | |
State | Published - 2001 |
ASJC Scopus subject areas
- Microbiology
- Immunology
- Insect Science
- Virology