Abstract
Chronic granulomatous disease (CGD) is characterized by life-threatening bacterial and fungal infections. Treatment with posaconazole led to a complete response in 7 of 8 patients with CGD with invasive mold infections (7 proven cases and 1 possible case) after failure or intolerance of treatment with standard antifungal agents. In this preliminary study, salvage treatment with posaconazole was safe and effective.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1684-1688 |
| Number of pages | 5 |
| Journal | Clinical Infectious Diseases |
| Volume | 40 |
| Issue number | 11 |
| DOIs | |
| State | Published - Jun 1 2005 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Immunology
Cite this
Posaconazole as salvage therapy in patients with chronic granulomatous disease and invasive filamentous fungal infection. / Segal, Brahm H.; Barnhart, Lisa A.; Anderson, Victoria L.; Walsh, Thomas J.; Malech, Harry L.; Holland, Steven M.
In: Clinical Infectious Diseases, Vol. 40, No. 11, 01.06.2005, p. 1684-1688.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Posaconazole as salvage therapy in patients with chronic granulomatous disease and invasive filamentous fungal infection
AU - Segal, Brahm H.
AU - Barnhart, Lisa A.
AU - Anderson, Victoria L.
AU - Walsh, Thomas J.
AU - Malech, Harry L.
AU - Holland, Steven M.
PY - 2005/6/1
Y1 - 2005/6/1
N2 - Chronic granulomatous disease (CGD) is characterized by life-threatening bacterial and fungal infections. Treatment with posaconazole led to a complete response in 7 of 8 patients with CGD with invasive mold infections (7 proven cases and 1 possible case) after failure or intolerance of treatment with standard antifungal agents. In this preliminary study, salvage treatment with posaconazole was safe and effective.
AB - Chronic granulomatous disease (CGD) is characterized by life-threatening bacterial and fungal infections. Treatment with posaconazole led to a complete response in 7 of 8 patients with CGD with invasive mold infections (7 proven cases and 1 possible case) after failure or intolerance of treatment with standard antifungal agents. In this preliminary study, salvage treatment with posaconazole was safe and effective.
UR - http://www.scopus.com/inward/record.url?scp=19344368837&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=19344368837&partnerID=8YFLogxK
U2 - 10.1086/430068
DO - 10.1086/430068
M3 - Article
C2 - 15889369
AN - SCOPUS:19344368837
VL - 40
SP - 1684
EP - 1688
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
SN - 1058-4838
IS - 11
ER -