Poor sleep quality and functional decline in older women

Adam P Spira, Kenneth Covinsky, George Rebok, Naresh M Punjabi, Katie L. Stone, Teresa A. Hillier, Kristine E. Ensrud, Kristine Yaffe

Research output: Contribution to journalArticle

Abstract

OBJECTIVES: To determine whether objectively measured sleep quality predicts 5-year incident instrumental activity of daily living (IADL) impairment and decline in grip strength and gait speed in older women. DESIGN: Prospective cohort. SETTING: Participants' homes, Study of Osteoporotic Fractures sites. PARTICIPANTS: Eight hundred seventeen women with a mean age of 82.4 at baseline. MEASUREMENTS: Participants completed 4.1 ± 0.7 nights of wrist actigraphy at baseline and measures of IADL impairment, grip strength, and gait speed at baseline and 5-year follow-up. RESULTS: After 5 years of follow-up, approximately 41% of participants had incident impairment in one or more IADLs. The quartile of women with the shortest total sleep time (TST) had 93% greater odds of incident IADL impairment than the longest sleepers (adjusted odds ratio (AOR) = 1.93, 95% confidence interval (CI) = 1.25-2.97). Similarly, the quartile of women with the lowest sleep efficiency (SE) had 65% greater odds of impairment than those with the highest (AOR = 1.65, 95% CI = 1.06-2.57). Women in the shortest TST quartile had twice the odds of declining grip strength as those with the longest TST (AOR = 1.97, 95% CI = 1.17-3.32). Finally, women in the quartiles with the most wake after sleep onset (WASO) and the lowest SE had approximately 90% greater odds of grip strength decline than those with the least WASO (AOR = 1.90, 95% CI = 1.11-3.24) and SE (AOR = 1.92, 95% CI = 1.12-3.29). CONCLUSION: Findings indicate that shorter sleep duration, greater WASO, and lower SE are risk factors for functional or physical decline in older women.

Original languageEnglish (US)
Pages (from-to)1092-1098
Number of pages7
JournalJournal of the American Geriatrics Society
Volume60
Issue number6
DOIs
StatePublished - Jun 2012

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Sleep
Hand Strength
Odds Ratio
Confidence Intervals
Activities of Daily Living
Actigraphy
Osteoporotic Fractures
Wrist

Keywords

  • Actigraphy
  • Function
  • IADLs
  • Sleep
  • Women

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Poor sleep quality and functional decline in older women. / Spira, Adam P; Covinsky, Kenneth; Rebok, George; Punjabi, Naresh M; Stone, Katie L.; Hillier, Teresa A.; Ensrud, Kristine E.; Yaffe, Kristine.

In: Journal of the American Geriatrics Society, Vol. 60, No. 6, 06.2012, p. 1092-1098.

Research output: Contribution to journalArticle

Spira, Adam P ; Covinsky, Kenneth ; Rebok, George ; Punjabi, Naresh M ; Stone, Katie L. ; Hillier, Teresa A. ; Ensrud, Kristine E. ; Yaffe, Kristine. / Poor sleep quality and functional decline in older women. In: Journal of the American Geriatrics Society. 2012 ; Vol. 60, No. 6. pp. 1092-1098.
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abstract = "OBJECTIVES: To determine whether objectively measured sleep quality predicts 5-year incident instrumental activity of daily living (IADL) impairment and decline in grip strength and gait speed in older women. DESIGN: Prospective cohort. SETTING: Participants' homes, Study of Osteoporotic Fractures sites. PARTICIPANTS: Eight hundred seventeen women with a mean age of 82.4 at baseline. MEASUREMENTS: Participants completed 4.1 ± 0.7 nights of wrist actigraphy at baseline and measures of IADL impairment, grip strength, and gait speed at baseline and 5-year follow-up. RESULTS: After 5 years of follow-up, approximately 41{\%} of participants had incident impairment in one or more IADLs. The quartile of women with the shortest total sleep time (TST) had 93{\%} greater odds of incident IADL impairment than the longest sleepers (adjusted odds ratio (AOR) = 1.93, 95{\%} confidence interval (CI) = 1.25-2.97). Similarly, the quartile of women with the lowest sleep efficiency (SE) had 65{\%} greater odds of impairment than those with the highest (AOR = 1.65, 95{\%} CI = 1.06-2.57). Women in the shortest TST quartile had twice the odds of declining grip strength as those with the longest TST (AOR = 1.97, 95{\%} CI = 1.17-3.32). Finally, women in the quartiles with the most wake after sleep onset (WASO) and the lowest SE had approximately 90{\%} greater odds of grip strength decline than those with the least WASO (AOR = 1.90, 95{\%} CI = 1.11-3.24) and SE (AOR = 1.92, 95{\%} CI = 1.12-3.29). CONCLUSION: Findings indicate that shorter sleep duration, greater WASO, and lower SE are risk factors for functional or physical decline in older women.",
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AU - Rebok, George

AU - Punjabi, Naresh M

AU - Stone, Katie L.

AU - Hillier, Teresa A.

AU - Ensrud, Kristine E.

AU - Yaffe, Kristine

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N2 - OBJECTIVES: To determine whether objectively measured sleep quality predicts 5-year incident instrumental activity of daily living (IADL) impairment and decline in grip strength and gait speed in older women. DESIGN: Prospective cohort. SETTING: Participants' homes, Study of Osteoporotic Fractures sites. PARTICIPANTS: Eight hundred seventeen women with a mean age of 82.4 at baseline. MEASUREMENTS: Participants completed 4.1 ± 0.7 nights of wrist actigraphy at baseline and measures of IADL impairment, grip strength, and gait speed at baseline and 5-year follow-up. RESULTS: After 5 years of follow-up, approximately 41% of participants had incident impairment in one or more IADLs. The quartile of women with the shortest total sleep time (TST) had 93% greater odds of incident IADL impairment than the longest sleepers (adjusted odds ratio (AOR) = 1.93, 95% confidence interval (CI) = 1.25-2.97). Similarly, the quartile of women with the lowest sleep efficiency (SE) had 65% greater odds of impairment than those with the highest (AOR = 1.65, 95% CI = 1.06-2.57). Women in the shortest TST quartile had twice the odds of declining grip strength as those with the longest TST (AOR = 1.97, 95% CI = 1.17-3.32). Finally, women in the quartiles with the most wake after sleep onset (WASO) and the lowest SE had approximately 90% greater odds of grip strength decline than those with the least WASO (AOR = 1.90, 95% CI = 1.11-3.24) and SE (AOR = 1.92, 95% CI = 1.12-3.29). CONCLUSION: Findings indicate that shorter sleep duration, greater WASO, and lower SE are risk factors for functional or physical decline in older women.

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