TY - JOUR
T1 - Poor Sleep in Inflammatory Bowel Disease Is Reflective of Distinct Sleep Disorders
AU - Salwen-Deremer, Jessica K.
AU - Smith, Michael T.
AU - Haskell, Hannah G.
AU - Schreyer, Colleen
AU - Siegel, Corey A.
N1 - Funding Information:
This work was supported by internal funding from the Departments of Psychiatry and Medicine (section of Gastroenterology and Hepatology) at Dartmouth-Hitchcock/Geisel School of Medicine at Dartmouth.
Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2022/7
Y1 - 2022/7
N2 - Background: Poor sleep is common in inflammatory bowel disease (IBD), predicting increased risk of flares, surgery, and/or hospitalization and reducing quality of life. Aims: To profile specific sleep disorder symptoms in IBD, informing intervention efforts. Methods: 312 adults with Crohn’s disease or ulcerative colitis were recruited from an academic medical center in New Hampshire, USA. Participants completed online surveys about sleep including well-validated measures of sleep quality, insomnia, restless leg syndrome, sleep apnea, and circadian rhythms. Participants also answered questions about IBD-related problems that could interfere with sleep. Results: 69.4% of participants reported experiencing poor sleep and 50% reported clinically significant insomnia. Participants with active IBD symptoms were more likely to have poor sleep and insomnia. Of those with poor sleep, 67.8% met the clinical threshold for insomnia disorder and 31.3% met criteria for two or more sleep disorders. IBD-related sleep disruptions (e.g., nighttime awakenings due to bowel movements) were not significantly related to poor sleep quality, but significantly related to insomnia severity for participants with active Crohn’s disease. Conclusions: While poor sleep in IBD is reflective of a number of different sleep problems, it is most frequently related to insomnia. IBD symptom severity contributes to insomnia, but insomnia is also distinct from IBD-related sleep disruptions. Future research on the treatment of insomnia disorder in particular in individuals with IBD is warranted.
AB - Background: Poor sleep is common in inflammatory bowel disease (IBD), predicting increased risk of flares, surgery, and/or hospitalization and reducing quality of life. Aims: To profile specific sleep disorder symptoms in IBD, informing intervention efforts. Methods: 312 adults with Crohn’s disease or ulcerative colitis were recruited from an academic medical center in New Hampshire, USA. Participants completed online surveys about sleep including well-validated measures of sleep quality, insomnia, restless leg syndrome, sleep apnea, and circadian rhythms. Participants also answered questions about IBD-related problems that could interfere with sleep. Results: 69.4% of participants reported experiencing poor sleep and 50% reported clinically significant insomnia. Participants with active IBD symptoms were more likely to have poor sleep and insomnia. Of those with poor sleep, 67.8% met the clinical threshold for insomnia disorder and 31.3% met criteria for two or more sleep disorders. IBD-related sleep disruptions (e.g., nighttime awakenings due to bowel movements) were not significantly related to poor sleep quality, but significantly related to insomnia severity for participants with active Crohn’s disease. Conclusions: While poor sleep in IBD is reflective of a number of different sleep problems, it is most frequently related to insomnia. IBD symptom severity contributes to insomnia, but insomnia is also distinct from IBD-related sleep disruptions. Future research on the treatment of insomnia disorder in particular in individuals with IBD is warranted.
KW - Colitis
KW - Crohn’s disease
KW - Inflammatory bowel diseases
KW - Sleep
KW - sleep disorders
KW - ulcerative
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U2 - 10.1007/s10620-021-07176-y
DO - 10.1007/s10620-021-07176-y
M3 - Article
C2 - 34331174
AN - SCOPUS:85111477676
SN - 0163-2116
VL - 67
SP - 3096
EP - 3107
JO - Digestive diseases and sciences
JF - Digestive diseases and sciences
IS - 7
ER -