Poor premorbid adjustment and CT scan abnormalities in chronic schizophrenia

D. R. Weinberger, E. Cannon-Spoor, S. G. Potkin, R. J. Wyatt

Research output: Contribution to journalArticlepeer-review


The authors evaluated the premorbid adjustment of 51 chronic schizophrenic patients by retrospective chart analysis using a novel scale. Those patients with CT evidence suggestive of brain atrophy had significantly worse premorbid scores, particularly during childhood, than did the patients with normal scans. This finding provides further support for the clinical relevance of CT findings in chronic schizophrenic patients and implicates a neuropathological process that occurs early in development.

Original languageEnglish (US)
Pages (from-to)1410-1413
Number of pages4
JournalAmerican Journal of Psychiatry
Issue number11
StatePublished - Jan 1 1980
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health


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