Pontine and cerebellar atrophy correlate with clinical disability in SCA2

S. H. Ying, S. I. Choi, S. L. Perlman, R. W. Baloh, D. S. Zee, A. W. Toga

Research output: Contribution to journalArticlepeer-review

Abstract

Spinocerebellar ataxia type 2 (SCA2) has protean manifestations, and a clinical marker of progression is needed. Although MRI is a promising tool, it is unclear whether the degree of atrophy shown on MRI is correlated with clinical dysfunction. Here the authors used high-resolution volumetric MRI analysis to show that cerebellar and pontine volumes specifically and closely correlate with functional staging scores.

Original languageEnglish (US)
Pages (from-to)424-426
Number of pages3
JournalNeurology
Volume66
Issue number3
DOIs
StatePublished - Feb 2006

ASJC Scopus subject areas

  • Clinical Neurology

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