Pontine and cerebellar atrophy correlate with clinical disability in SCA2

S. H. Ying, S. I. Choi, S. L. Perlman, R. W. Baloh, D. S. Zee, A. W. Toga

Research output: Contribution to journalArticle

Abstract

Spinocerebellar ataxia type 2 (SCA2) has protean manifestations, and a clinical marker of progression is needed. Although MRI is a promising tool, it is unclear whether the degree of atrophy shown on MRI is correlated with clinical dysfunction. Here the authors used high-resolution volumetric MRI analysis to show that cerebellar and pontine volumes specifically and closely correlate with functional staging scores.

Original languageEnglish (US)
Pages (from-to)424-426
Number of pages3
JournalNeurology
Volume66
Issue number3
DOIs
StatePublished - Feb 1 2006

ASJC Scopus subject areas

  • Clinical Neurology

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  • Cite this

    Ying, S. H., Choi, S. I., Perlman, S. L., Baloh, R. W., Zee, D. S., & Toga, A. W. (2006). Pontine and cerebellar atrophy correlate with clinical disability in SCA2. Neurology, 66(3), 424-426. https://doi.org/10.1212/01.wnl.0000196464.47508.00