Abstract
Four mutants of polyoma virus lacking endonuclease HindII site I were isolated and characterized with respect to the VP1 coding sequence. Three of these mutants had deletions that removed 0.2 to 0.3% of the genome. All three deletion mutants encoded VP1 proteins that were smaller than wild type and that lacked one or more tryptic peptides normally found in the wild-type VP1 protein. Our results suggest that Hind II site I is at, or very near, the carboxy terminal end of the coding sequence for VP1. A model for the peptide organization in that region is presented.
Original language | English (US) |
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Pages (from-to) | 515-522 |
Number of pages | 8 |
Journal | Journal of virology |
Volume | 30 |
Issue number | 2 |
DOIs | |
State | Published - 1979 |
Externally published | Yes |
ASJC Scopus subject areas
- Microbiology
- Immunology
- Insect Science
- Virology