Polymorphonuclear leukocytes: Possible mechanism of accumulation in psoriasis

Gerald S. Lazarus, Fred J. Yost, Charlotte A. Thomas

Research output: Contribution to journalArticlepeer-review

Abstract

Extracts of involved and uninvolved skin from nine patients with untreated psoriasis were studied for chemotactic activity. Psoriatic plaque contains increased amounts of a complement-dependent chemotactic factor that is inhibited by diisopropyl fluorophosphate. This factor may be human skin serine proteinase.

Original languageEnglish (US)
Pages (from-to)1162-1163
Number of pages2
JournalScience
Volume198
Issue number4322
DOIs
StatePublished - 1977
Externally publishedYes

ASJC Scopus subject areas

  • General

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