Polymorphisms of dopamine receptor and transporter genes and hallucinations in Parkinson's disease

Jian Wang, Chunying Zhao, Biao Chen, Zhuo Lin Liu

Research output: Contribution to journalArticlepeer-review

Abstract

The authors conducted a case-control study of Parkinson's disease patients with and without visual hallucinations to investigate associations of the polymorphisms of the dopamine receptors D2 32806 C>T (Taq1A), D3 Ser 9Gly and Msp1, D5 978T>C and dopamine transporter 3′-UTR 40 bp VNTR with visual hallucinations in Parkinson's disease. No significant differences were found between hallucinators and non-hallucinators in either the genotypic or allelic distributions. Our data suggest that the loci investigated here are not associated with the visual hallucinogenesis in Parkinson's disease.

Original languageEnglish (US)
Pages (from-to)193-196
Number of pages4
JournalNeuroscience Letters
Volume355
Issue number3
DOIs
StatePublished - Jan 30 2004

Keywords

  • Dopamine
  • Gene polymorphism
  • Hallucination
  • Parkinson's disease
  • Receptor
  • Transporter

ASJC Scopus subject areas

  • Neuroscience(all)

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