Polymorphisms in the human SNAIL (SNAI1) gene

K. Okajima, W. A. Paznekas, T. Burstyn, E. W. Jabs

Research output: Contribution to journalArticle

Abstract

The human SNAIL is an important developmental protein involved in the formation of mesoderm and neural crest. The protein contains three classic and one atypical zinc-finger motif. The SNAI1 gene is composed of three exons. We have identified three SNPs in non-coding regions, two in the 5′UTR and one in intron 1, which can be detected by PCR followed by restriction enzyme digestion. We also identified a GGG/GGGG polymorphism in intron 1. We screened CEPH DNAs for these polymorphisms.

Original languageEnglish (US)
Pages (from-to)53-55
Number of pages3
JournalMolecular and Cellular Probes
Volume15
Issue number1
DOIs
StatePublished - 2001

Fingerprint

Introns
Neural Crest
Zinc Fingers
Mesoderm
Genes
Single Nucleotide Polymorphism
Digestion
Exons
Proteins
Polymerase Chain Reaction
DNA
Enzymes

Keywords

  • Single nucleotide polymorphism (SNP)
  • Snail
  • Zinc finger protein

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Okajima, K., Paznekas, W. A., Burstyn, T., & Jabs, E. W. (2001). Polymorphisms in the human SNAIL (SNAI1) gene. Molecular and Cellular Probes, 15(1), 53-55. https://doi.org/10.1006/mcpr.2000.0332

Polymorphisms in the human SNAIL (SNAI1) gene. / Okajima, K.; Paznekas, W. A.; Burstyn, T.; Jabs, E. W.

In: Molecular and Cellular Probes, Vol. 15, No. 1, 2001, p. 53-55.

Research output: Contribution to journalArticle

Okajima, K, Paznekas, WA, Burstyn, T & Jabs, EW 2001, 'Polymorphisms in the human SNAIL (SNAI1) gene', Molecular and Cellular Probes, vol. 15, no. 1, pp. 53-55. https://doi.org/10.1006/mcpr.2000.0332
Okajima, K. ; Paznekas, W. A. ; Burstyn, T. ; Jabs, E. W. / Polymorphisms in the human SNAIL (SNAI1) gene. In: Molecular and Cellular Probes. 2001 ; Vol. 15, No. 1. pp. 53-55.
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