Polycythemia in the newborn

Juan I. Remon, Aarti Raghavan, Akhil Maheshwari

Research output: Contribution to journalReview articlepeer-review

Abstract

Neonatal polycythemia, defined as a venous hematocrit ≥65% (0.65), is a common problem in newborns. Infants born postterm or small for gestational age, infants of diabetic mothers, recipient twins in twin-to-twin transfusion syndrome, and those who have chromosomal abnormalities are at higher risk. Although the cause of polycythemia is often multifactorial, most cases can be classified as having active (increased fetal erythropoiesis) or passive (erythrocyte transfusion) polycythemia. By increasing blood viscosity, polycythemia can impair microcirculatory flow in end organs and can present with neurologic, cardiopulmonary, gastrointestinal, and metabolic symptoms. In this article, we review the pathophysiology, clinical presentation, diagnosis, and management of polycythemia in the newborn.

Original languageEnglish (US)
Pages (from-to)e20-e28
JournalNeoReviews
Volume12
Issue number1
DOIs
StatePublished - Jan 1 2011
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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