TY - JOUR
T1 - Polyamines
T2 - New cues in cellular signal transduction
AU - Bachrach, Uriel
AU - Wang, Yong Chun
AU - Tabib, Amalia
PY - 2001/6
Y1 - 2001/6
N2 - The naturally occurring polyamines putrescine, spermidine, and spermine are involved in signal transduction. This has been demonstrated by using inhibitors for polyamine biosynthesis (such as α-difluoromethylornithine) or adding polyamines to cultured cells. Different polyamines, preferentially activated protein kinases (tyrosine kinases and MAP kinases), stimulated the expression of nuclear protooncogenes (myc, jun, and fos).
AB - The naturally occurring polyamines putrescine, spermidine, and spermine are involved in signal transduction. This has been demonstrated by using inhibitors for polyamine biosynthesis (such as α-difluoromethylornithine) or adding polyamines to cultured cells. Different polyamines, preferentially activated protein kinases (tyrosine kinases and MAP kinases), stimulated the expression of nuclear protooncogenes (myc, jun, and fos).
UR - http://www.scopus.com/inward/record.url?scp=0035354580&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035354580&partnerID=8YFLogxK
U2 - 10.1152/physiologyonline.2001.16.3.106
DO - 10.1152/physiologyonline.2001.16.3.106
M3 - Article
C2 - 11443226
AN - SCOPUS:0035354580
SN - 0886-1714
VL - 16
SP - 106
EP - 109
JO - News in Physiological Sciences
JF - News in Physiological Sciences
IS - 3
ER -