Point: Should positive end-expiratory pressure in patients with ARDS be set on oxygenation? Yes\No

Russell R. Miller, Neil R. MacIntyre, R. Duncan Hite, Jonathon D. Truwit, Roy G. Brower, Alan H. Morris, Gregory A. Schmidt

Research output: Contribution to journalEditorial

Abstract

Complex techniques of managing PEEP, such as with analysis of PV relationships, suffer from several important limitations. Infl ection points on the PV curve are not tightly linked to alveolar recruitment. Moreover, these PV strategies are time consuming, diffi cult to interpret, and have yet to affect clinical outcomes. In contrast, PEEP/FIO 2 tables provide a reasonable treatment strategy, are clinically easy to use, and are amenable to widespread application. We conclude that best current ventilator practice in patients with ALI/ARDS includes a PEEP/FIO 2 table as part of a low tidal volume strategy (≤6 mL/kg predicted body weight). Although imperfect, PEEP/FIO 2 tables are a reasonable approach.

Original languageEnglish (US)
Pages (from-to)1379-1382
Number of pages4
JournalCHEST
Volume141
Issue number6
DOIs
StatePublished - Jun 2012

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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    Miller, R. R., MacIntyre, N. R., Hite, R. D., Truwit, J. D., Brower, R. G., Morris, A. H., & Schmidt, G. A. (2012). Point: Should positive end-expiratory pressure in patients with ARDS be set on oxygenation? Yes\No. CHEST, 141(6), 1379-1382. https://doi.org/10.1378/chest.12-0155