Abstract
With a view to determining the role of diabetic serum factor (DSF) in the progression of membrane pathology, time-dependent preincubation effects of DSF on certain membrane-bound enzymes of normal polymorphonuclear leucocytes (PMNL) have been studied. DSF is found to cause significant decrements in the activities of Na+/K+ ATPase, PLC and AcE of PMNL on in vitro incubation for 60 min, while the effect on Ca2+/Mg2+ ATPase appears only on prolonged incubation with an initial hike in activity at 5 min. The implications of these results have been discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 244-246 |
| Number of pages | 3 |
| Journal | Indian journal of biochemistry & biophysics |
| Volume | 30 |
| Issue number | 4 |
| State | Published - Aug 1993 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biophysics
- Biochemistry