Platelet Function Testing in Clinical Practice - Experience and Views from Europe and the US

Thomas O. Bergmeijer, Jochem Wouter van Werkum, Udaya S. Tantry, Paul A. Gurbel, Jrien M. ten Berg

Research output: Contribution to journalArticlepeer-review

Abstract

A 68-year-old male is admitted to our hospital because of a 50-minute episode of chest pain occurring during the night. On admission he is symptom-free. His electrocardiogram shows new negative T waves in the leads V1-V3. Troponin T, measured twice, with a six-hour interval, is negative. His previous history mentions diabetes mellitus type II, hypercholesterolaemia and obesity (110 kg/176 cm/body mass index 35). He is treated with aspirin (300 mg loading dose, then 80 mg/day), clopidogrel (600 mg loading dose, then 75 mg/day), fondaparinux (2.5 mg subcutaneously/day) and metoprolol (100 mg/day). He is scheduled to undergo coronary angiography the next day. The question is: should we measure platelet function and/or genetics in this patient?.

Original languageEnglish (US)
Pages (from-to)203-211
Number of pages9
JournalEuropean Cardiology
Volume7
Issue number3
DOIs
StatePublished - Jun 2011

Keywords

  • Coronary angiography
  • Dual antiplatelet therapy
  • Percutaneous coronary intervention
  • Platelet function testing

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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