Abstract
Levels of platelet-associated IgG (PA-IgG) were studied in 72 patients with Hodgkin's (HD) and non-Hodgkin's lymphoma (NHL). Thirty-nine percent of patients with HD and 20% of patients with NHL had elevated PA-IgG levels. There was a positive correlation between disease activity and the presence of PA-IgG in HD and NHL. In patients with HD, PA-IgG strongly correlated with extent of disease and may serve as a marker of disease activity. PA-IgG may have facilitated platelet destruction in 5 of 11 thrombocytopenic patients with HD and increased PA-IgG and in 2 patients with HD and increased PA-IgG who developed severe thrombocytopenia when treated with chemotherapy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 944-948 |
| Number of pages | 5 |
| Journal | Blood |
| Volume | 63 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1984 |
ASJC Scopus subject areas
- Biochemistry
- Immunology
- Hematology
- Cell Biology