Platelet-associated IgG in patients with lymphoma

A. W. Berkman, Thomas Stephen Kickler, H. Braine

Research output: Contribution to journalArticle

Abstract

Levels of platelet-associated IgG (PA-IgG) were studied in 72 patients with Hodgkin's (HD) and non-Hodgkin's lymphoma (NHL). Thirty-nine percent of patients with HD and 20% of patients with NHL had elevated PA-IgG levels. There was a positive correlation between disease activity and the presence of PA-IgG in HD and NHL. In patients with HD, PA-IgG strongly correlated with extent of disease and may serve as a marker of disease activity. PA-IgG may have facilitated platelet destruction in 5 of 11 thrombocytopenic patients with HD and increased PA-IgG and in 2 patients with HD and increased PA-IgG who developed severe thrombocytopenia when treated with chemotherapy.

Original languageEnglish (US)
Pages (from-to)944-948
Number of pages5
JournalBlood
Volume63
Issue number4
StatePublished - 1984

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Platelets
Lymphoma
Blood Platelets
Immunoglobulin G
Hodgkin Disease
Non-Hodgkin's Lymphoma
Chemotherapy
Thrombocytopenia
Drug Therapy

ASJC Scopus subject areas

  • Hematology

Cite this

Berkman, A. W., Kickler, T. S., & Braine, H. (1984). Platelet-associated IgG in patients with lymphoma. Blood, 63(4), 944-948.

Platelet-associated IgG in patients with lymphoma. / Berkman, A. W.; Kickler, Thomas Stephen; Braine, H.

In: Blood, Vol. 63, No. 4, 1984, p. 944-948.

Research output: Contribution to journalArticle

Berkman, AW, Kickler, TS & Braine, H 1984, 'Platelet-associated IgG in patients with lymphoma', Blood, vol. 63, no. 4, pp. 944-948.
Berkman AW, Kickler TS, Braine H. Platelet-associated IgG in patients with lymphoma. Blood. 1984;63(4):944-948.
Berkman, A. W. ; Kickler, Thomas Stephen ; Braine, H. / Platelet-associated IgG in patients with lymphoma. In: Blood. 1984 ; Vol. 63, No. 4. pp. 944-948.
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