Platelet aggregation in Hyperapobetalipoproteinemia

M. Miller, W. Bell, S. Plano, J. Connors, S. Kennedy, P. Kwiterovich

Research output: Contribution to journalArticlepeer-review

Abstract

Hyperapobetalipoproteinemia (HyperapoB) is a lipid disorder characterized by premature coronary disease, although the mechanisms have not been elucidated. Because abnormalities in platelet function may represent an enhanced susceptibility to coronary thrombosis, the aggregability of platelets was examined in hyperapoB subjects. Compared to controls, there were no significant differences in either platelet lipid composition or in aggregation to epinephrine, ADP, or collagen. In contrast to other dyslipidemias, platelet function does not appear to be abnormal in this well defined lipid disorder.

Original languageEnglish (US)
Pages (from-to)209-211
Number of pages3
JournalAmerican journal of hematology
Volume37
Issue number3
DOIs
StatePublished - Jul 1991

Keywords

  • aggregation
  • lipid disorder
  • platelets

ASJC Scopus subject areas

  • Hematology

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