TY - JOUR
T1 - Plasmodium ovale wallikeri and P. ovale curtisi Infections and Diagnostic Approaches to Imported Malaria, France, 2013-2018
AU - French National Reference Center for Imported Malaria Study Group
AU - Joste, Valentin
AU - Bailly, Justine
AU - Hubert, Véronique
AU - Pauc, Cécile
AU - Gendrot, Mathieu
AU - Guillochon, Emilie
AU - Madamet, Marylin
AU - Thellier, Marc
AU - Kendjo, Eric
AU - Argy, Nicolas
AU - Pradines, Bruno
AU - Houzé, Sandrine
AU - Garabedian, Chantal
AU - Domergue, Alain
AU - Clauser, Sylvain
AU - Agnamey, Patrice
AU - Damiani, Céline
AU - de Gentile, Ludovic
AU - Pihet, Marc
AU - Marfaing-Koka, Anne
AU - Marteau, Anthony
AU - Arezki, Izri
AU - Ficko, Cecile
AU - Larréché, Sébastien
AU - Angoulvant, Adela Enache
AU - Guennouni, Nadia
AU - Pistone, Thierry
AU - Fuster-Dumas, Valérie
AU - Malvy, Denis
AU - Quinio, Dorothée
AU - Nevez, Gilles
AU - Raffenot, Didier
AU - Rogeaux, Olivier
AU - Nourrisson, Céline
AU - Dahane, Naima
AU - Li, Angèle
AU - Cuisenier, Bernadette
AU - Basmacyan, Louise
AU - Motard-Picheloup, Annie
AU - Garnaud, Cécile
AU - Dard, Céline
AU - Maubon, Dominique
AU - Dannaoui, Eric
AU - Botterel, Françoise
AU - Bemba, Dieudonné
AU - Poilane, Isabelle
AU - Mendes-Moreira, Ana
AU - Pean-De-Ponfilly, Gauthier
AU - Megarbane, Bruno
AU - Bloc'h, Martine
N1 - Publisher Copyright:
© 2021 Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2021/2
Y1 - 2021/2
N2 - We retrospectively analyzed epidemiologic, clinical, and biologic characteristics of 368 Plasmodium ovale wallikeri and 309 P. ovale curtisi infections treated in France during January 2013-December 2018. P. ovale wallikeri infections displayed deeper thrombocytopenia and shorter latency periods. Despite similar clinical manifestations, P. ovale wallikeri-infected patients were more frequently treated with artemisinin-based combination therapy. Although the difference was not statistically significant, P. ovale wallikeri-infected patients were 5 times more frequently hospitalized in intensive care or intermediate care and had a higher proportion of severe thrombocytopenia than P. ovale curtisi-infected patients. Rapid diagnostic tests that detect aldolase were more efficient than those detecting Plasmodium lactate dehydrogenase. Sequence analysis of the potra gene from 90 P. ovale isolates reveals an insufficient polymorphism for relapse typing.
AB - We retrospectively analyzed epidemiologic, clinical, and biologic characteristics of 368 Plasmodium ovale wallikeri and 309 P. ovale curtisi infections treated in France during January 2013-December 2018. P. ovale wallikeri infections displayed deeper thrombocytopenia and shorter latency periods. Despite similar clinical manifestations, P. ovale wallikeri-infected patients were more frequently treated with artemisinin-based combination therapy. Although the difference was not statistically significant, P. ovale wallikeri-infected patients were 5 times more frequently hospitalized in intensive care or intermediate care and had a higher proportion of severe thrombocytopenia than P. ovale curtisi-infected patients. Rapid diagnostic tests that detect aldolase were more efficient than those detecting Plasmodium lactate dehydrogenase. Sequence analysis of the potra gene from 90 P. ovale isolates reveals an insufficient polymorphism for relapse typing.
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U2 - 10.3201/eid2702.202143
DO - 10.3201/eid2702.202143
M3 - Review article
C2 - 33496652
AN - SCOPUS:85100231061
SN - 1080-6040
VL - 27
SP - 372
EP - 384
JO - Emerging infectious diseases
JF - Emerging infectious diseases
IS - 2
ER -