Plasmodium falciparum transmission rate and selection for drug resistance: A vexed association or a key to successful control?

S. Mharakurwa

Research output: Contribution to journalArticlepeer-review

Abstract

While malaria eradication campaigns once adopted a combination of vector control and chemotherapy to overcome the disease, today's opinion on the matter is equivocal. So what has changed? This paper reviews some of the confusing hypotheses on the relationship between Plasmodium falciparum transmission and levels of drug resistance. New field evidence showing variations of in vivo chloroquine resistance in relation to indoor residual spraying and natural endemicity patterns, is considered with a view to how these phenomena implicate on control.

Original languageEnglish (US)
Pages (from-to)1483-1487
Number of pages5
JournalInternational Journal for Parasitology
Volume34
Issue number13-14
DOIs
StatePublished - Dec 1 2004

Keywords

  • Drug resistance
  • Malaria transmission
  • Vector control

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

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