Plasmapheresis, intravenous cytomegalovirus-specific immunoglobulin and reversal of antibody-mediated rejection in a pediatric renal transplant recipient: A case report

Susan Furth, A. M. Neu, J. Hart, A. Zachary, P. Colombani, B. A. Fivush

Research output: Contribution to journalArticle

Abstract

This is a pediatric case report illustrating the development of antibody (Ab)-mediated rejection in a patient with low levels of pretransplant anti- human leucocyte antigen (HLA) panel reactive antibodies (PRA). The clinical course of this patient suggests that aggressive use of a combination of plasmapheresis, monoclonal anti-T-lymphocyte antibody therapy, and intravenous immunoglobulin (IVIG) therapy can reverse Ab-mediated rejection in previously allosensitized pediatric transplant recipients.

Original languageEnglish (US)
Pages (from-to)146-149
Number of pages4
JournalPediatric transplantation
Volume3
Issue number2
DOIs
StatePublished - May 1 1999

Keywords

  • Intravenous immunoglobulin
  • Pediatrics
  • Plasmapheresis
  • Rejection
  • Renal transplantation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Transplantation

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