Plasma membrane sphingomyelin hydrolysis increases hippocampal neuron excitability by sphingosine-1-phosphate mediated mechanisms

Medicine & Life Sciences

• Sphingomyelin Phosphodiesterase 85%
• sphingosine 1-phosphate 82%
• Sphingomyelins 78%
• Hydrolysis 58%
• Cell Membrane 46%
• Neurons 39%
• ceramide 1-phosphate 34%
• Action Potentials 28%
• sphingosine kinase 15%
• Neurotransmitter Receptor 12%
• Ceramides 12%
• Membrane Lipids 11%
• Ion Channels 10%
• Lipid Metabolism 10%
• Synapses 9%
• Mass Spectrometry 9%
• Enzymes 5%
• Population 4%
• Proteins 3%

Chemical Compounds

• Sphingosine 1-Phosphate 100%
• Sphingomyelin 78%
• Ceramide 46%
• Hydrolysis 39%
• Plasma 39%
• Pharmacological Metabolism 19%
• Sphingosine 17%
• Neurotransmitter 14%
• Lipid 8%
• Application 7%
• Environment 7%
• Protein 5%
• Ion 4%