Plaque formation and purification of BK virus in cultured human urinary cells

G. H. Sack, J. S. Felix, A. A. Lanahan

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Abstract

Primary human urinary cells support growth and plaque formation by papovavirus BK, permitting plaque purification of the virus. After plaquing, the virus forms uniform plaques and its DNA has a homogeneous restriction enzyme fragment profile. Support of BK replication as well as morphological and cultural characteristics suggest an epithelial origin for the cells.

Original languageEnglish (US)
Pages (from-to)185-189
Number of pages5
JournalJournal of General Virology
Volume50
Issue number1
StatePublished - Dec 1 1980

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ASJC Scopus subject areas

  • Virology

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