Plaque characteristics in the superficial femoral artery correlate with walking impairment questionnaire scores in peripheral arterial disease: The Walking and leg Circulation Study (WALCS) iii

Mary M. McDermott, Kiang Liu, Timothy J. Carroll, Melina Kibbe, Luigi Ferrucci, Jack M. Guralnik, Mark Morasch, William Pearce, James Carr, Chun Yuan, Christopher M. Kramer, Lu Tian, Yihua Liao, Debiao Li, Michael H. Criqui

Research output: Contribution to journalArticle

Abstract

Purpose: We studied associations of magnetic resonance imaging (MRI)-measured plaque area and relative percent lumen reduction in the proximal superficial femoral artery with Walking Impairment Questionnaire (WIQ) scores and quality of life in people with lower extremity peripheral arterial disease (PAD). Methods: Four-hundred forty-two participants with PAD underwent cross-sectional imaging of the proximal superficial femoral artery with MRI, and completed the WIQ and the Short-Form-12 mental and physical functioning questionnaires. Questionnaires were scored on a 0-100 scale (100=best). Results: adjust for age, sex, race, the ankle brachial index (ABI), comorbidities, and other covariates. Results Adjusting for age, sex, race, ABI, comorbidities, and other covariates, higher mean plaque area was associated with poorer WIQ distance scores (1st quintile (least plaque)-44.8, 2nd quintile-43.3, 3rd quintile-38.9, 4th quintile-34.6, 5th quintile (greatest plaque)-30.6, p trend

Original languageEnglish (US)
Pages (from-to)148-157
Number of pages10
JournalJournal of Surgical Radiology
Volume3
Issue number3
StatePublished - 2012
Externally publishedYes

Fingerprint

Peripheral Arterial Disease
Femoral Artery
Walking
Leg
Ankle Brachial Index
Comorbidity
Magnetic Resonance Imaging
Lower Extremity
Quality of Life
Surveys and Questionnaires

Keywords

  • Atherosclerotic plaque
  • Intermittent claudication
  • Peripheral arterial disease
  • Physical functioning

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Surgery

Cite this

Plaque characteristics in the superficial femoral artery correlate with walking impairment questionnaire scores in peripheral arterial disease : The Walking and leg Circulation Study (WALCS) iii. / McDermott, Mary M.; Liu, Kiang; Carroll, Timothy J.; Kibbe, Melina; Ferrucci, Luigi; Guralnik, Jack M.; Morasch, Mark; Pearce, William; Carr, James; Yuan, Chun; Kramer, Christopher M.; Tian, Lu; Liao, Yihua; Li, Debiao; Criqui, Michael H.

In: Journal of Surgical Radiology, Vol. 3, No. 3, 2012, p. 148-157.

Research output: Contribution to journalArticle

McDermott, MM, Liu, K, Carroll, TJ, Kibbe, M, Ferrucci, L, Guralnik, JM, Morasch, M, Pearce, W, Carr, J, Yuan, C, Kramer, CM, Tian, L, Liao, Y, Li, D & Criqui, MH 2012, 'Plaque characteristics in the superficial femoral artery correlate with walking impairment questionnaire scores in peripheral arterial disease: The Walking and leg Circulation Study (WALCS) iii', Journal of Surgical Radiology, vol. 3, no. 3, pp. 148-157.
McDermott, Mary M. ; Liu, Kiang ; Carroll, Timothy J. ; Kibbe, Melina ; Ferrucci, Luigi ; Guralnik, Jack M. ; Morasch, Mark ; Pearce, William ; Carr, James ; Yuan, Chun ; Kramer, Christopher M. ; Tian, Lu ; Liao, Yihua ; Li, Debiao ; Criqui, Michael H. / Plaque characteristics in the superficial femoral artery correlate with walking impairment questionnaire scores in peripheral arterial disease : The Walking and leg Circulation Study (WALCS) iii. In: Journal of Surgical Radiology. 2012 ; Vol. 3, No. 3. pp. 148-157.
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AU - Criqui, Michael H.

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KW - Intermittent claudication

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