TY - JOUR
T1 - Plaque characteristics in the superficial femoral artery correlate with walking impairment questionnaire scores in peripheral arterial disease
T2 - The Walking and leg Circulation Study (WALCS) iii
AU - McDermott, Mary M.
AU - Liu, Kiang
AU - Carroll, Timothy J.
AU - Kibbe, Melina
AU - Ferrucci, Luigi
AU - Guralnik, Jack M.
AU - Morasch, Mark
AU - Pearce, William
AU - Carr, James
AU - Yuan, Chun
AU - Kramer, Christopher M.
AU - Tian, Lu
AU - Liao, Yihua
AU - Li, Debiao
AU - Criqui, Michael H.
PY - 2012
Y1 - 2012
N2 - Purpose: We studied associations of magnetic resonance imaging (MRI)-measured plaque area and relative percent lumen reduction in the proximal superficial femoral artery with Walking Impairment Questionnaire (WIQ) scores and quality of life in people with lower extremity peripheral arterial disease (PAD). Methods: Four-hundred forty-two participants with PAD underwent cross-sectional imaging of the proximal superficial femoral artery with MRI, and completed the WIQ and the Short-Form-12 mental and physical functioning questionnaires. Questionnaires were scored on a 0-100 scale (100=best). Results: adjust for age, sex, race, the ankle brachial index (ABI), comorbidities, and other covariates. Results Adjusting for age, sex, race, ABI, comorbidities, and other covariates, higher mean plaque area was associated with poorer WIQ distance scores (1st quintile (least plaque)-44.8, 2nd quintile-43.3, 3rd quintile-38.9, 4th quintile-34.6, 5th quintile (greatest plaque)-30.6, p trend
AB - Purpose: We studied associations of magnetic resonance imaging (MRI)-measured plaque area and relative percent lumen reduction in the proximal superficial femoral artery with Walking Impairment Questionnaire (WIQ) scores and quality of life in people with lower extremity peripheral arterial disease (PAD). Methods: Four-hundred forty-two participants with PAD underwent cross-sectional imaging of the proximal superficial femoral artery with MRI, and completed the WIQ and the Short-Form-12 mental and physical functioning questionnaires. Questionnaires were scored on a 0-100 scale (100=best). Results: adjust for age, sex, race, the ankle brachial index (ABI), comorbidities, and other covariates. Results Adjusting for age, sex, race, ABI, comorbidities, and other covariates, higher mean plaque area was associated with poorer WIQ distance scores (1st quintile (least plaque)-44.8, 2nd quintile-43.3, 3rd quintile-38.9, 4th quintile-34.6, 5th quintile (greatest plaque)-30.6, p trend
KW - Atherosclerotic plaque
KW - Intermittent claudication
KW - Peripheral arterial disease
KW - Physical functioning
UR - http://www.scopus.com/inward/record.url?scp=84871255291&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84871255291&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:84871255291
SN - 2156-213X
VL - 3
SP - 148
EP - 157
JO - Journal of Surgical Radiology
JF - Journal of Surgical Radiology
IS - 3
ER -