TY - JOUR
T1 - Planimetric rate of healing in venous ulcers of the leg treated with pressure bandage and hydrocolloid dressing
AU - Margolis, David J.
AU - Gross, Edward A.
AU - Wood, Collette R.
AU - Lazarus, Gerald S.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1993
Y1 - 1993
N2 - Background: Venous leg ulcers are a common cause of morbidity, but few predictive parameters exist that can be used to follow their progress. Objective: We investigated the use of healing rate as a useful parameter in the treatment of venous ulceration. Methods: Twenty–seven venous ulcers being treated with a standard regimen were evaluated. We calculated the initial (4-week) and overall healing rates using the Gilman method (ΔA/p). Results: The average initial healing rate for all ulcers combined, the healed group, and the nonhealing group was 0.069, 0.087, and −0.005 cm/wk, respectively. Similarly, the average overall healing rate for all ulcers combined, the healed group, and the nonhealing group was 0.062, 0.089, and −0.043 cm/wk, respectively. Conclusion: The initial healing rate (ΔA/p0–4) may be an appropriate end point for clinical investigations comparing therapies for the treatment of chronic venous leg ulcers.
AB - Background: Venous leg ulcers are a common cause of morbidity, but few predictive parameters exist that can be used to follow their progress. Objective: We investigated the use of healing rate as a useful parameter in the treatment of venous ulceration. Methods: Twenty–seven venous ulcers being treated with a standard regimen were evaluated. We calculated the initial (4-week) and overall healing rates using the Gilman method (ΔA/p). Results: The average initial healing rate for all ulcers combined, the healed group, and the nonhealing group was 0.069, 0.087, and −0.005 cm/wk, respectively. Similarly, the average overall healing rate for all ulcers combined, the healed group, and the nonhealing group was 0.062, 0.089, and −0.043 cm/wk, respectively. Conclusion: The initial healing rate (ΔA/p0–4) may be an appropriate end point for clinical investigations comparing therapies for the treatment of chronic venous leg ulcers.
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U2 - 10.1016/0190-9622(93)70061-W
DO - 10.1016/0190-9622(93)70061-W
M3 - Article
C2 - 8445057
AN - SCOPUS:0027466220
SN - 0190-9622
VL - 28
SP - 418
EP - 421
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 3
ER -