Pituitary tumor apoplexy

Philip C. Johnston, Amir H. Hamrahian, Robert J. Weil, Laurence Kennedy

Research output: Contribution to journalReview article


We review the etiology, investigations, management and outcomes of pituitary tumor apoplexy. Pituitary tumor apoplexy is a clinical syndrome which typically includes the acute onset of headache and/or visual disturbance, cranial nerve palsy and partial or complete endocrine dysfunction. It is associated with either infarction or hemorrhage of a pre-existing pituitary adenoma and is associated with significant morbidity and potential fatality. Not all patients will present with classic signs and symptoms, therefore it is pertinent to appreciate the clinical spectrum in which this condition can present.

Original languageEnglish (US)
Pages (from-to)939-944
Number of pages6
JournalJournal of Clinical Neuroscience
Issue number6
StatePublished - Jun 1 2015
Externally publishedYes


  • Apoplexy
  • Cranial nerve palsy
  • Hypopituitarism
  • Pituitary adenoma
  • Visual fields

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

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