Pituitary adenomas: Possible role of bromocriptine in intratumoral hemorrhage

David Mark Yousem, J. A. Arrington, Simion J Zinreich, A. J. Kumar, R. N. Bryan

Research output: Contribution to journalArticle

Abstract

Magnetic resonance (MR) images of 68 patients examined for adenomas of the pituitary gland were retrospectively reviewed for the presence of hyperintensity on T1-weighted images because of recent reports suggesting that bromocriptine treatment may affect T1 values. Twenty-seven patients were examined after either surgery or radiation therapy, 29 were receiving bromocriptine, and 22 had not received any treatment at the time of MR imaging. MR imaging criteria showed evidence of subacute or chronic evidence of subacute or chronic intratumoral hemorrhage in 18 patients, five of whom had hemorrhage proved at surgery. Ten of the 18 patients were asymptomatic from the hemorrhage; eight had headaches, visual field cuts, or cranial nerve deficits. Although an increased frequency of intratumoral hemorrhage was noted in prolactinomas and macroadenomas and in patients undergoing bromocripine therapy, the effect of bromocriptine on bleeding was the only significant correlation (P <.01).

Original languageEnglish (US)
Pages (from-to)239-243
Number of pages5
JournalRadiology
Volume170
Issue number1 I
StatePublished - 1989

Fingerprint

Bromocriptine
Pituitary Neoplasms
Hemorrhage
Magnetic Resonance Imaging
Prolactinoma
Cranial Nerves
Pituitary Gland
Visual Fields
Adenoma
Headache
Magnetic Resonance Spectroscopy
Radiotherapy
Therapeutics

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Yousem, D. M., Arrington, J. A., Zinreich, S. J., Kumar, A. J., & Bryan, R. N. (1989). Pituitary adenomas: Possible role of bromocriptine in intratumoral hemorrhage. Radiology, 170(1 I), 239-243.

Pituitary adenomas : Possible role of bromocriptine in intratumoral hemorrhage. / Yousem, David Mark; Arrington, J. A.; Zinreich, Simion J; Kumar, A. J.; Bryan, R. N.

In: Radiology, Vol. 170, No. 1 I, 1989, p. 239-243.

Research output: Contribution to journalArticle

Yousem, DM, Arrington, JA, Zinreich, SJ, Kumar, AJ & Bryan, RN 1989, 'Pituitary adenomas: Possible role of bromocriptine in intratumoral hemorrhage', Radiology, vol. 170, no. 1 I, pp. 239-243.
Yousem, David Mark ; Arrington, J. A. ; Zinreich, Simion J ; Kumar, A. J. ; Bryan, R. N. / Pituitary adenomas : Possible role of bromocriptine in intratumoral hemorrhage. In: Radiology. 1989 ; Vol. 170, No. 1 I. pp. 239-243.
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